Introduction -- Epidemiology of suicide -- Issues in measurement of suicide risk factors in adults -- Issues in measurement of risk factors in youth -- Social and cultural factors in suicide risk -- Neurobiology of teenage and adult suicide: possible biological markers for identification of suicidal patients -- Strategies to identify genes for complex diseases -- Neurobiological consequences of childhood abuse and neglect -- Association of early physical or sexual abuse with suicide attempts in bipolar illness -- Psychologic factors in suicide.