Advanced topics on radiosensitizers of hypoxic cells.
General Material Designation
[Book]
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
[Place of publication not identified]
Name of Publisher, Distributor, etc.
Springer-Verlag New York
Date of Publication, Distribution, etc.
2013
CONTENTS NOTE
Text of Note
The Chemistry of Nitroimidazole Hypoxic Cell Radiosensitizers.- Molecular Structure and Biological Activity of Hypoxic Cell Radiosensitizers and Hypoxic-Specific Cytotoxins.- Physico-Chemical Methods for Investigating Mechanisms of Radiosensitization.- Radiation-Induced and Metabolism-Induced Reactions of Hypoxic Sensitizers with Cellular Molecules.- Radiation-Induced Cellular DNA Damage and Repair, and the Effect of Hypoxic Cell Radiosensitizers.- Biological Methods for Studying Radiosensitization.- Lipophilicity and the Pharmacokinetics of Nitroimidazoles.- Pharmacokinetic Studies on Some Novel (2-nitro-1-imidazolyl) Propanolamine Radiosensitizers.- The Effect of Dexamethasone on the Neurotoxicity of Nitroimidazole Compounds.- Radiosensitizers with Hyperfractionation in Radiotherapy.- The Design of Clinical Trials and Clinical Toxicology of the Nitroimidazole Misonidazole in Phase I Testing in the Radiation Therapy Oncology Group.- Misonidazole Clinical Trials in the United States Radiation Therapy Oncology Group (RTOG).- Misonidazole and Desmethylmisonidazole in Clinical Radiotherapy.- Prospects for New Hypoxic Cell Radiosensitizers.- Round Table on Clinical Sensitizer Research in Italy: Clinical Experiments with Radiosensitizing Drugs in Italy.- Multiple Daily Fractionation (MDF) in Association with Misonidazole (MIS): A Two-Year Experience with Head and Neck Cancer.- Clinical Trials and Preliminary Results Obtained by Association of Electroaffinic Hypoxic Cell Radiosensitizing Drugs (Misonidazole and Metronidazole) with Radiotherapy (Telecobalt Therapy) for the Treatment of Some Types of Neoplastic Diseases at a Locally Advanced Stage.- Control of the Immunological Status of Neoplastic Patients undergoing Telecobalt Therapy in Association with Radiosensitizers.- The Association of Radiotherapy with Radiosensitizing Drugs in the Treatment of Soft Tissue Sarcomas (Preliminary Studies).- List of Participants.