In Vitro StudiesIn Vitro Approaches to Site-Specific Imaging Agents, Raymond E. GibsonSmall Animal StudiesSmall Animal Tumor Models for Use in Imaging, Cheryl L. MarksAnimal Models in Cardiology, Wengen Chen, Henry Gewirtz, Mark Smith, and Vasken DilsizianImaging Diabetes in Small Animals: Models, Methods, and Targets, Kooresh I. ShoghiRadiopharmacology and RadiopharmacyTargeted Radiopharmaceuticals: Advances in Radiopharmacology and Radiopharmacy, Cathy S. Cutler and Sally W. SchwarzCase Studies on Developing Targeted Non-Nuclear ProbesTargeted Optical Molecular Imaging with Cytate: From Bench Toward Bedside, Yang Liu and Samuel AchilefuMolecular Imaging of P-Selectin with Contrast Ultrasound for the Detection of Recent Tissue Ischemia, Brian Davidson and Jonathan R. LindnerThe Evolution of Magnetic Nanoparticles: From Imaging to Therapy, Yali Li and Jason R. McCarthyCase Studies on Developing Targeted RadiotracersTargeting Prostate Cancer with Small Molecule Inhibitors of Prostate Specific Membrane Antigen, John W. Babich, John L. Joyal, and R. Edward ColemanImaging Infection Based on Expression of Thymidine Kinase, Chetan Bettegowda, Youngjoo Byun, Catherine A. Foss, George Sgouros, Richard F. Ambinder, and Martin G. PomperDesign Criteria for Targeted Molecules: Muscarinic Cholinergic Systems Biology, William C. EckelmanRadioligands for the Vesicular Monoamine Transporter Type 2, Michael R. KilbournRadiopharmaceuticals for Imaging Proliferation, Kenneth A. Krohn, John R. Grierson, Mark Muzi, and Jeffrey L. Schwartz[99mTc]TRODAT: Dopamine Transporter (DAT) Imaging Agent for SPECT, Hank F. Kung and Karl PloesslDevelopment of Radiotracers and Fluorescent Probes for Imaging Sigma-2 Receptors In Vitro and In Vivo, Robert H. MachSteroid Hormone Ligands for the Estrogen Receptor, David A. Mankoff, Jeanne M. Link, and Hannah M. LindenTargeting Norepinephrine Transporters in Cardiac Sympathetic Nerve Terminals, David M. RaffelPET Quantification of Myocardial Metabolism: Challenges and Opportunities, Arun K. Thukkani and Robert J. GroplerDevelopment of Receptor-Avid Peptide Radiotracers for Targeting Human Cancers, Wynn A. Volkert, Thomas P. Quinn, C. Jeffrey Smith, and Timothy J. Hoffman
Covering the fundamental concepts of molecular imaging, this work addresses basic principles, disease models, imaging studies in animals, imaging in initial human studies, and the application of molecular imaging in pharmacy and drug discovery. Topics are presented in logical progression, from basic concepts to applications. The text includes examples from human studies with imaging of breast cancer, cardiovascular disease, and neurodegenerative diseases. The book is a valuable tool for readers involved with molecular imaging, biomedical imaging, radiology, medical physics, medicinal chemistry, and pharmacology--Provided by publisher.