عنوان

The gastrointestinal circulation /

شابک

1615041184

شابک

9781615041183

شابک اشتباه

1615041176

شابک اشتباه

9781615041176

شماره

b776006

عنوان اصلي

The gastrointestinal circulation /

نام عام مواد

[Book]

نام نخستين پديدآور

Peter R. Kvietys.

محل نشرو پخش و غیره

San Rafael, Calif. :

نام ناشر، پخش کننده و غيره

Morgan & Claypool Life Sciences,

تاریخ نشرو بخش و غیره

©2010.

نام خاص و کميت اثر

1 online resource (xi, 127 pages) :

ساير جزييات

illustrations.

عنوان فروست

Integrated systems physiology: from molecule to function,

مشخصه جلد

bk. #5

شاپا ي ISSN فروست

1947-945X ;

متن يادداشت

Includes bibliographical references (pages 95-126).

متن يادداشت

Introduction -- Anatomy -- Regulation of Vascular Tone and Oxygenation -- Extrinsic Vasoregulation: Neural and Humoral -- Postprandial Hyperemia -- Transcapillary Solute Exchange -- Transcapillary Fluid Exchange -- Interaction of Capillary and Interstitial Forces -- Gastrointestinal Circulation and Mucosal Defense -- Gastrointestinal Circulation and Mucosal Pathology I:Ischemia/Reperfusion -- Gastrointestinal Circulation and Mucosal Pathology II: Chronic Portal Hypertension.

بدون عنوان

0

متن يادداشت

The microcirculation of the gastrointestinal tract is under the control of both myogenic and metabolic regulatory systems. The myogenic mechanism contributes to basal vascular tone and the regulation of transmural pressure, while the metabolic mechanism is responsible for maintaining an appropriate balance between O₂ demand and O₂ delivery. In the postprandial state, hydrolytic products of food digestion elicit a hyperemia, which serves to meet the increased O2 demand of nutrient assimilation. Metabolically linked factors (e.g., tissue pO₂, adenosine) are primarily responsible for this functional hyperemia. The fenestrated capillaries of the gastrointestinal mucosa are relatively permeable to small hydrolytic products of food digestion (e.g., glucose), yet restrict the transcapillary movement of larger molecules (e.g., albumin). This allows for the absorption of hydrolytic products of food digestion without compromising the oncotic pressure gradient governing transcapillary fluid movement and edema formation. The gastrointestinal microcirculation is also an important component of the mucosal defense system whose function is to prevent (and rapidly repair) inadvertent epithelial injury by potentially noxious constituents of chyme. Two pathological conditions in which the gastrointestinal circulation plays an important role are ischemia/reperfusion and chronic portal hypertension. Ischemia/reperfusion results in mucosal edema and disruption of the epithelium due, in part, to an inflammatory response (e.g., increase in capillary permeability to macromolecules and neutrophil infiltration). Chronic portal hypertension results in an increase in gastrointestinal blood flow due to an imbalance in vasodilator and vasoconstrictor influences on the microcirculation.

عنوان

Gastrointestinal circulation.

شماره استاندارد بين المللي کتاب و موسيقي

9781615041176

موضوع مستند نشده

Gastroenterology.

موضوع مستند نشده

Gastrointestinal system-- Blood-vessels.

موضوع مستند نشده

Digestive System.

موضوع مستند نشده

Microcirculation.

موضوع مستند نشده

Gastroenterology.

موضوع مستند نشده

MEDICAL-- Nutrition.

موضوع مستند نشده

MED-- 060000

شماره

ويراست

شماره رده

نشانه اثر

شماره رده

شماره رده

مستند نام اشخاص تاييد نشده

Kvietys, Peter R.

تاريخ عمليات

20201203084737.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y