عنوان

The role of model integration in complex systems modelling :

شابک

1280009284

شابک

3642156029

شابک

3642156037

شابک

9781280009280

شابک

9783642156021

شابک

9783642156038

شابک اشتباه

9783642156021

شماره

b765094

عنوان اصلي

The role of model integration in complex systems modelling :

نام عام مواد

[Book]

ساير اطلاعات عنواني

an example from cancer biology /

نام نخستين پديدآور

Manish Patel, Sylvia Nagl.

محل نشرو پخش و غیره

London :

نام ناشر، پخش کننده و غيره

Springer,

تاریخ نشرو بخش و غیره

2010.

نام خاص و کميت اثر

1 online resource (x, 168 pages) :

ساير جزييات

illustrations

عنوان فروست

Understanding complex systems

متن يادداشت

Includes bibliographical references (pages 153-163) and index.

متن يادداشت

Nature to numbers: complex systems modelling of cancer -- Coping with complexity: modelling of complex systems -- Novel strategies for integrating models into systems-level simulations -- Experiments in model integration.

بدون عنوان

0

متن يادداشت

Model integration - the process by which different modelling efforts can be brought together to simulate the target system - is a core technology in the field of Systems Biology. In the work presented here model integration was addressed directly taking cancer systems as an example. An in-depth literature review was carried out to survey the model forms and types currently being utilised. This was used to formalise the main challenges that model integration poses, namely that of paradigm (the formalism on which a model is based), focus (the real-world system the model represents) and scale. A two-tier model integration strategy, including a knowledge-driven approach to address model semantics, was developed to tackle these challenges. In the first step a novel description of models at the level of behaviour, rather than the precise mathematical or computational basis of the model, is developed by distilling a set of abstract classes and properties. These can accurately describe model behaviour and hence describe focus in a way that can be integrated with behavioural descriptions of other models. In the second step this behaviour is decomposed into an agent-based system by translating the models into local interaction rules. The book provides a detailed and highly integrated presentation of the method, encompassing both its novel theoretical and practical aspects, which will enable the reader to practically apply it to their model integration needs in academic research and professional settings. The text is self-supporting. It also includes an in-depth current bibliography to relevant research papers and literature. The review of the current state of the art in tumour modelling provides added value.

منبع سفارش / آدرس اشتراک

Springer

شماره انبار

978-3-642-15602-1

عنوان

Role of model integration in complex systems modelling.

شماره استاندارد بين المللي کتاب و موسيقي

9783642156021

موضوع مستند نشده

Cancer-- Mathematical models.

موضوع مستند نشده

Cancer-- Research-- Methodology.

موضوع مستند نشده

Models, Theoretical.

موضوع مستند نشده

Neoplasms.

موضوع مستند نشده

Research Design.

موضوع مستند نشده

Biologisches System

موضوع مستند نشده

Cancer-- Mathematical models.

موضوع مستند نشده

Komplexes System

موضوع مستند نشده

Krebs

موضوع مستند نشده

Mathematisches Modell

موضوع مستند نشده

Physique.

موضوع مستند نشده

GPFC.

موضوع مستند نشده

TEC000000.

شماره

ويراست

شماره رده

نشانه اثر

شماره رده

شماره رده

مستند نام اشخاص تاييد نشده

Patel, Manish I.

مستند نام اشخاص تاييد نشده

Nagl, Sylvia.

تاريخ عمليات

20201206104307.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y