یادداشتهای مربوط به کتابنامه ، واژه نامه و نمایه های داخل اثر
متن يادداشت
Includes bibliographical references and index.
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
The steroid / nuclear receptor superfamily is a large and growing group of transcription factors that are studied by a large and varied number of basic and clinical researchers. The first two chapters describe the evolutionary biology of the superfamily and explain how to clone and characterize new receptors. Chapter 3 shows how to identify the ligands of novel receptors and chapter 4 explains the kinetic analysis of receptor interactions. In chapter 5, the reader is guided through the functional characterization of coactivators using microinjection. The next section covers receptor phosphorylation, ligand regulated transcription, and hormone resistance syndromes. Chapter 9 describes the in vitro assembly of Hsp90 complexes and chapter 10 explains yeast as a model system for looking at receptor function. The final chapter shows how heterologous proteins can be regulated by fusion to the hormone binding domain of a receptor. Nuclear Receptors: A Practical Approach is a comprehensive guide to studying members of the superfamily and will be invaluable to all researchers old and new.
ویراست دیگر از اثر در قالب دیگر رسانه
عنوان
Nuclear receptors.
شماره استاندارد بين المللي کتاب و موسيقي
0199637423
موضوع (اسم عام یاعبارت اسمی عام)
موضوع مستند نشده
Nuclear receptors (Biochemistry)
موضوع مستند نشده
Steroid hormones-- Receptors.
موضوع مستند نشده
Transcription factors.
موضوع مستند نشده
Receptors, Cytoplasmic and Nuclear, Laboratory Manuals.