عنوان

Tumor models in cancer research /

شابک

1607619687

شابک

9781607619680

شابک اشتباه

1607619679

شابک اشتباه

9781607619673

شماره

b700723

عنوان اصلي

Tumor models in cancer research /

نام عام مواد

[Book]

نام نخستين پديدآور

Beverly A. Teicher, editor.

وضعيت ويراست

2nd ed.

محل نشرو پخش و غیره

New York :

نام ناشر، پخش کننده و غيره

Springer,

تاریخ نشرو بخش و غیره

©2011.

نام خاص و کميت اثر

1 online resource (xiv, 693 pages) :

ساير جزييات

illustrations (some color)

عنوان فروست

Cancer drug discovery and development

متن يادداشت

Includes bibliographical references and index.

متن يادداشت

Perspectives on the history and evolution of tumor models -- Murine L1210 and P388 leukemias -- Transplantable syngeneic rodent tumors: solid tumors in mice -- B16 murine melanoma: historical perspective on the development of a solid tumor model -- Human tumor xenograft efficacy models -- Imaging the steps of metastasis at the macro and cellular level with fluorescent proteins in real time -- Patient-derived tumor models and explants -- The pediatric preclinical testing program -- Imaging efficacy in tumor models -- Mammary cancer in rats -- Animal models of melanoma -- Experimental animal models for investigating renal cell carcinoma pathogenesis and preclinical therapeutic approaches -- Animal models of mesothelioma -- The use of mouse models to study leukemia/lymphoma and assess therapeutic approaches -- Spontaneous companion animal (pet) cancers -- Genetically engineered mouse models of pancreatic ductal adenocarcinoma -- Transgenic adenocarcinoma of the mouse prostate: a validated model for the identification and characterization of molecular targets and the evaluation of therapeutic agents -- The utility of transgenic mouse models for cancer prevention research -- Models for evaluation of targeted therapies of invasive and metastatic disease -- Animal models of toxicities caused by anti-neoplastic therapy -- Bone marrow as a critical normal tissue that limits drug dose/exposure in preclinical models and the clinic -- Anesthetic considerations for the study of murine tumor models -- Preclinical tumor response end points -- Tumor cell survival -- Apoptosis in vivo -- Transparent window models and intravital microscopy: imaging gene expression, physiological function and therapeutic effects in tumors.

بدون عنوان

0

متن يادداشت

Beverly A. Teicher and a panel of leading experts comprehensively describe the state-of-the-art in animal tumor model research. This volume updates and extends the comprehensive presentations in the first edition. The wide array of models detailed form the basis for the selection of compounds and treatments that go into clinical testing of patients, and include syngeneic models, human tumor xenograft models, orthotopic models, metastatic models, and genetically engineered mouse models. Synthesizing many years experience with all the major in vivo models currently available for the study of malignant disease, Tumor Models in Cancer Research 2nd edition, provides preclinical and clinical cancer researchers alike with a comprehensive guide to the selection of these models, their effective use, and the optimal interpretation of their results.

منبع سفارش / آدرس اشتراک

Springer

شماره انبار

978-1-60761-967-3

عنوان

Tumor models in cancer research.

شماره استاندارد بين المللي کتاب و موسيقي

9781607619673

عنوان

Springer eBooks

موضوع مستند نشده

Cancer cells.

موضوع مستند نشده

Oncology, Experimental.

موضوع مستند نشده

Tumors-- Animal models.

موضوع مستند نشده

Animals.

موضوع مستند نشده

Antineoplastic Agents-- pharmacology.

موضوع مستند نشده

Disease Models, Animal.

موضوع مستند نشده

Drug Evaluation, Preclinical.

موضوع مستند نشده

Mice.

موضوع مستند نشده

Models, Biological.

موضوع مستند نشده

Neoplasms-- drug therapy.

موضوع مستند نشده

Cancer cells.

موضوع مستند نشده

HEALTH & FITNESS-- Diseases-- Cancer.

موضوع مستند نشده

Médecine.

موضوع مستند نشده

MEDICAL-- Oncology.

موضوع مستند نشده

Oncology, Experimental.

موضوع مستند نشده

Tumors-- Animal models.

موضوع مستند نشده

HEA-- 039030

موضوع مستند نشده

MED-- 062000

موضوع مستند نشده

MJCL

شماره

ويراست

شماره رده

شماره رده

نشانه اثر

نشانه اثر

شماره رده

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

Teicher, Beverly A.,1952-

تاريخ عمليات

20201207163039.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y