عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
شماره کتابشناسی ملی
شماره
LA51q4c622
زبان اثر
زبان متن نوشتاري يا گفتاري و مانند آن
انگلیسی
عنوان و نام پديدآور
عنوان اصلي
A Subset of Brain Neurons Controls a Sexually Dimorphic Proboscis Holding Behavior in Adult Drosophilia Melanogaster
نام عام مواد
[Article]
نام نخستين پديدآور
Ahmad, Sameera; Amin, Kush; Chen, Yu-Chieh David; Dahanukar, Anupama
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
Taste is essential for humans and animals alike to evaluate food quality and make important decisionsabout food choice and intake. How complex brains process sensory information to produce behavioris an essential question in the field of sensory neurobiology. Currently, little is known about tastecircuits in the brain as compared to other sensory systems. Here, we used the common vinegar fly,Drosophila melanogaster, to explore the potential role of brain neurons labeled by a transgenic line(VT041723-GAL4) in producing "proboscis holding" behavior (extrusion of the mouthpart withoutwithdrawal). By utilizing the GAL4/UAS binary expression system, we expressed a heat-activatedcation channel (UAS-dTrpA1) in these brain neurons and artificially activated them by elevationof temperature, subsequently examining behavior in the heat-activated proboscis extension reflex(PER) assay. We found that activation of these neurons induced proboscis holding. Interestingly, theproboscis holding phenotype was sexually dimorphic. Male flies rarely showed proboscis holdingand those that did had shorter proboscis holding durations. On the other hand, both mated and virginfemales showed significantly more proboscis holding and had longer proboscis holding durationsthan male flies. Overall, we identified a subset of brain neurons labeled by the VT041723-GAL4 linethat controls a sexually dimorphic feeding response (proboscis holding) upon activation.
مجموعه
تاريخ نشر
2018
عنوان
UC Riverside Undergraduate Research Journal
شماره جلد
12/1
نام شخص به منزله سر شناسه - (مسئولیت معنوی درجه اول )
عنصر شناسه اي
Ahmad, Sameera; Amin, Kush; Chen, Yu-Chieh David; Dahanukar, Anupama
دسترسی و محل الکترونیکی
نام الکترونيکي
مطالعه متن کتاب اطلاعات رکورد کتابشناسی
نوع ماده
[Article]
کد کاربرگه
275578
اطلاعات دسترسی رکورد
سطح دسترسي
a
تكميل شده
Y
