Toxic epidermal necrolysis after radiotherapy for pleomorphic liposarcoma
نام عام مواد
[Article]
نام نخستين پديدآور
Esaa, Fatema S; Hobson, Julia G; Matar, Regina N; Prieto, Peter A; Somers, Kathryn E
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are life-threatening, cutaneous reactions often associated with culprit drugs. A growing body of knowledge has deepened our understanding of the pathophysiology and clarified mechanisms such as drug-specific cytotoxicity mediated by T-cells, genetic linkage with HLA and non-HLA genes, TCR restriction, and cytotoxicity mechanisms. Physicians should broadly consider the etiology of SJS/TEN in order to better understand treatment strategies as well as identify which patients may be at risk for developing this condition. Mechanisms for how radiotherapy and rare malignancies may contribute to the development of TEN and SJS have been proposed.
مجموعه
تاريخ نشر
2020
عنوان
Dermatology Online Journal
شماره جلد
26/1
نام شخص به منزله سر شناسه - (مسئولیت معنوی درجه اول )
عنصر شناسه اي
Esaa, Fatema S; Hobson, Julia G; Matar, Regina N; Prieto, Peter A; Somers, Kathryn E