Primary cutaneous Epstein-Barr virus-positive diffuse large B-cell lymphoma (DLBCL) in a patient taking fingolimod
نام عام مواد
[Article]
نام نخستين پديدآور
Wills, Abby; Fan, Guang; Kim, Edward; Okada, Craig Y; White, Kevin P; Hopkins, R Samuel
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
A 55-year-old man with relapsing-remitting multiple sclerosis on fingolimod presented to the dermatology clinic with skin lesions on the left temple and cheek. Histopathology showed a diffuse infiltrate of enlarged, atypical lymphocytes throughout the dermis with an overlying grenz zone and a subpopulation of scattered smaller lymphocytes and plasma cells. Epstein-Barr virus-encoded RNA in situ hybridization stain was positive. Based on the morphologic and immunophenotypic findings, a diagnosis of EBV-positive diffuse large B-cell lymphoma was made. This case aims to raise awareness for the dermatologist that patients on fingolimod may be at increased risk of lymphoproliferative disorders.
مجموعه
تاريخ نشر
2019
عنوان
Dermatology Online Journal
شماره جلد
25/9
نام شخص به منزله سر شناسه - (مسئولیت معنوی درجه اول )
عنصر شناسه اي
Wills, Abby; Fan, Guang; Kim, Edward; Okada, Craig Y; White, Kevin P; Hopkins, R Samuel