عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
شماره کتابشناسی ملی
شماره
LA23x1k44q
عنوان و نام پديدآور
عنوان اصلي
Feasibility of combination allogeneic stem cell therapy for spinal cord injury:
نام عام مواد
[Article]
نام نخستين پديدآور
Ichim, Thomas E; Solano, Fabio; Lara, Fabian; Paris, Eugenia; Ugalde, Federico; Rodriguez, Jorge; Minev, Boris; Bogin, Vladimir; Ramos, Famela; Woods, Erik J; Murphy, Michael P; Patel, Amit N; Harman, Robert J; Riordan, Neil H
عنوان اصلي به قلم نويسنده ديگر
a case report
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
Abstract Cellular therapy for spinal cord injury (SCI) is overviewed focusing on bone marrow mononuclear cells, olfactory ensheathing cells, and mesenchymal stem cells. A case is made for the possibility of combining cell types, as well as for allogeneic use. We report the case of 29 year old male who suffered a crush fracture of the L1 vertebral body, lacking lower sensorimotor function, being a score A on the ASIA scale. Stem cell therapy comprised of intrathecal administration of allogeneic umbilical cord blood ex-vivo expanded CD34 and umbilical cord matrix MSC was performed 5 months, 8 months, and 14 months after injury. Cell administration was well tolerated with no adverse effects observed. Neuropathic pain subsided from intermittent 10/10 to once a week 3/10 VAS. Recovery of muscle, bowel and sexual function was noted, along with a decrease in ASIA score to "D". This case supports further investigation into allogeneic-based stem cell therapies for SCI.
مجموعه
تاريخ نشر
2010
عنوان
UC San Diego
دسترسی و محل الکترونیکی
نام الکترونيکي
مطالعه متن کتاب اطلاعات رکورد کتابشناسی
نوع ماده
[Article]
کد کاربرگه
275578
اطلاعات دسترسی رکورد
سطح دسترسي
a
تكميل شده
Y
