عنوان

In vivo isolation of the effects of melanin from underlying hemodynamics across skin types using spatial frequency domain spectroscopy.

شماره

LA6203n73j

عنوان اصلي

In vivo isolation of the effects of melanin from underlying hemodynamics across skin types using spatial frequency domain spectroscopy.

نام عام مواد

[Article]

نام نخستين پديدآور

Saager, Rolf B; Sharif, Ata; Kelly, Kristen M; Durkin, Anthony J

متن يادداشت

Skin is a highly structured tissue, raising concerns as to whether skin pigmentation due to epidermal melanin may confound accurate measurements of underlying hemodynamics. Using both venous and arterial cuff occlusions as a means of inducing differential hemodynamic perturbations, we present analyses of spectra limited to the visible or near-infrared regime, in addition to a layered model approach. The influence of melanin, spanning Fitzpatrick skin types I to V, on underlying estimations of hemodynamics in skin as interpreted by these spectral regions are assessed. The layered model provides minimal cross-talk between melanin and hemodynamics and enables removal of problematic correlations between measured tissue oxygenation estimates and skin phototype.

تاريخ نشر

2016

عنوان

UC Irvine

نام الکترونيکي

نوع ماده

[Article]

کد کاربرگه

275578

سطح دسترسي

a

تكميل شده

Y