عنوان

Genomics-driven healthcare :

شابک

9789811075056

شابک

9789811075063

شابک

9811075050

شابک

9811075069

شابک اشتباه

9789811075056

عنوان اصلي

Genomics-driven healthcare :

نام عام مواد

[Book]

ساير اطلاعات عنواني

trends in disease prevention and treatment /

نام نخستين پديدآور

Yashwant Pathak, editor.

محل نشرو پخش و غیره

Singapore :

نام ناشر، پخش کننده و غيره

Adis,

تاریخ نشرو بخش و غیره

2018.

نام خاص و کميت اثر

1 online resource (xv, 409 pages) :

ساير جزييات

illustrations (some color)

متن يادداشت

Intro; Foreword; Preface; Omics-Driven Trends in Disease Prevention and Better Healthcare; Contents; Contributors; 1: Rethinking Drug Discovery and Targeting After the Genomic Revolution; 1.1 Introduction; 1.2 Genomic Revolution; 1.3 Changing Scenario in Drug Discovery and Targeting; 1.3.1 A New Pattern for Drug Development in the Form of Pharmacogenomics; 1.3.2 Personalized Medicine for Individual Genomes; 1.4 Paradigm Shift in the Treatment of Disease in the Postgenomic Era; 1.4.1 Shift in Treatment and Drug Development for Cancer

متن يادداشت

1.4.2 Shift in Treatment and Drug Development for Cardiovascular Disease1.4.3 Shift in Treatment and Drug Development for Tuberculosis; References; 2: Living Between Sickness and Health: Where Is the Human Genome Leading Us?; 2.1 Introduction; 2.2 Cancer; 2.2.1 Lung Cancer; 2.2.2 Breast Cancer; 2.2.3 Prostate Cancer; 2.2.4 Colorectal Cancer; 2.3 Cardiovascular System; 2.3.1 Coronary Heart Disease; 2.3.2 Pulmonary Arterial Hypertension; 2.3.3 Stroke; 2.3.4 Dyslipidemia; 2.4 Mental Illness; 2.4.1 Depression/Bipolar Disorder; 2.4.2 Parkinson's Disease; 2.4.3 Alzheimer's Disease

متن يادداشت

2.4.4 SchizophreniaReferences; 3: Pharmacogenomics: Setting Newer Paradigms of Genetics in Therapy and Medicine; 3.1 Introduction; 3.2 Pharmacogenomics: Genetic Variability and Pharmacokinetics; 3.3 Pharmacogenetics and Drug Pharmacodynamics; 3.4 Different Types of Genetic Polymorphisms and Their Impact on Pharmacotherapy; 3.4.1 Single-Nucleotide Polymorphisms (SNPs); 3.4.2 Noncoding Region Polymorphisms; 3.4.2.1 Promoter Polymorphism; 3.4.2.2 5' and 3' UTR Polymorphism; 3.4.2.3 Splice Site Polymorphism; 3.4.2.4 Short Tandem Repeat Polymorphism

متن يادداشت

3.4.2.5 Insertion/Deletion Polymorphism (Indels)3.5 Technologies of Pharmacogenomics; 3.6 Clinical Relevance of Pharmacogenomics; 3.6.1 Side Effects and Toxicity; 3.6.2 Therapeutic Efficacy; 3.7 Applications of Pharmacogenomics; 3.7.1 Pharmacogenomics: Improving Productivity of Drug Development Process; 3.7.2 Pharmacogenomics: Establishing Drug Safety; 3.7.3 Pharmacogenomics: Development of Molecular Diagnostics; 3.7.4 Pharmacogenomics: Application for Personalized Medicine; 3.8 Pharmacogenomics and Its Impact on Pharmaceutical Market; 3.8.1 Market Segmentation

متن يادداشت

3.8.2 Market Expansion3.9 Challenges of Pharmacogenomics; 3.9.1 Financing Personalized Healthcare; 3.9.2 Ethical and Legal Issues; 3.9.3 Scientific Uncertainty; 3.10 Future Prospects of Pharmacogenomics; References; 4: Bioinformatics and Pharmacogenomics: Tools to Understand and Accelerate Infectious Disease Control; 4.1 Introduction; 4.2 Infectious Diseases Scenario in Developing Countries; 4.3 Need for Developing Bioinformatics Tools; 4.4 Clinical Bioinformatics; 4.5 Bioinformatics Tools for Population Science Study; 4.5.1 Google Trends

بدون عنوان

0

بدون عنوان

8

بدون عنوان

8

بدون عنوان

8

بدون عنوان

8

متن يادداشت

This book evaluates trends arising in "--Omics" sciences in terms of their current and potential future application to therapeutic design and understanding of disease. Chapters consider the impact of pharmacogenomics and bioinformatics on drug development, as well as trends in genomics, as applied to understanding of neurodegenerative and lung disease, psychiatry and oncology. Following the genome studies released in early part of this century, the advent of the -Omics sciences (genomics and pharmacogenomics, proteomics, metabolomics, transcriptomics) has seen the expansion of a vast knowledgebase with utility in preventing and treating disease, and improving health for all. Bioinformatics and improved pharmacogenetic understanding forge a path for improved drug discovery and design methods accounting for differences in delivery and disposition across populations.

منبع سفارش / آدرس اشتراک

Springer Nature

شماره انبار

com.springer.onix.9789811075063

شماره استاندارد بين المللي کتاب و موسيقي

9789811075056

موضوع مستند نشده

Medical genetics.

موضوع مستند نشده

Pharmacogenomics.

موضوع مستند نشده

Medical genetics.

موضوع مستند نشده

Pharmacogenomics.

موضوع مستند نشده

MED072000

موضوع مستند نشده

TDC

موضوع مستند نشده

TDCW

شماره

ويراست

شماره رده

مستند نام اشخاص تاييد نشده

Pathak, Yashwant

تاريخ عمليات

20200823221940.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y