عنوان

Test No. 412: Subacute Inhalation Toxicity: 28-Day Study /

شابک

9264070788

شابک

9789264070783

عنوان اصلي

Test No. 412: Subacute Inhalation Toxicity: 28-Day Study /

نام عام مواد

[Book]

نام نخستين پديدآور

Organisation for Economic Co-operation and Development.

محل نشرو پخش و غیره

[Paris] :

نام ناشر، پخش کننده و غيره

OECD Publishing,

تاریخ نشرو بخش و غیره

2009.

نام خاص و کميت اثر

1 online resource (14 pages)

عنوان فروست

OECD Guidelines for the Testing of Chemicals, Section 4: Health Effects,

شاپا ي ISSN فروست

2074-5788

متن يادداشت

This revised Test Guideline 412 (TG 412) has been designed to fully characterize test article toxicityby the inhalation route following repeated exposure for a limited period of time (28 days), and to provide data for quantitative inhalation risk assessments. Groups of at least 5 male and 5 female rodents are exposed 6 hours per day for 28 days to a) the test article at three or more concentration levels, b) filtered air (negative control), and/or c) the vehicle (vehicle control). Animals are generally exposed 5 days per week but exposure for 7 days per week is also allowed. Males and females arealways tested, but they may be exposed at different concentration levels if it is known that one sex ismore susceptible to a given test article. This guideline allows the study director the flexibility toinclude satellite (reversibility) groups, bronchoalveolar lavage (BAL), neurologic tests, and additionalclinical pathology and histopathological evaluations in order to better characterize the toxicity of a testarticle.

عنوان

Essai n⁰ 412 : Toxicité subaigüe par inhalation : étude sur 28 jours

شماره استاندارد بين المللي کتاب و موسيقي

9789264070790

موضوع مستند نشده

Chemical tests and reagents.

موضوع مستند نشده

Chemical tests and reagents.

مستند نام تنالگان تاييد نشده

Organisation for Economic Co-operation and Development.

تاريخ عمليات

20200823214252.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y