1. Introduction 2. From Bright's Disease to Chronic Kidney Disease 3. Classification of Chronic Kidney Disease -- Historic Perspective: From Insufficiency and Failure to Chronic Kidney Disease 4. Assessing Kidney Function 5. Clinical Assessment and Management of Chronic Kidney Disease Across its Stages 6. Epidemiology of Chronic Kidney Disease: Scope of the Problem 7. Gender Issues in Chronic Kidney Disease 8. The Uremic Syndrome 9. The Pathophysiology of Proteinuria 10. Protein Energy Metabolism in Chronic Kidney Disease 11. Aging and the Kidney: Clinical and Pathophysiological Issues 12. Pathophysiology of Progression: Organ and Cellular Considerations 13. Pathophysiology of Diabetic Nephropathy 14. Pathophysiology of Hypertension in Chronic Kidney Disease 15. Chronic Kidney Disease and Vascular Endothelium 16. Cardiovascular Disease and Chronic Kidney Disease 17. Inflammation in Chronic Kidney Disease 19. Psychosocial Issues in Chronic Kidney Disease Patients 20. Ophthalmic Issues in Chronic Kidney Disease 21. Neurologic Complications of Chronic Kidney Disease 22. Hematologic Complications of Chronic Kidney Disease: Erythrocytes and Platelets 23. Hematologic Complications of Chronic Kidney Disease: Leukocyte and Monocyte Function 24. Immune Function in Chronic Kidney Disease 25. Chronic Kidney Disease and Gastrointestinal Disorders 26. Endocrine Complications of Chronic Kidney Disease 27. Disorders of Mineral and Bone Metabolism in Chronic Kidney Disease 28. Sleep and Sleep Disorders in Chronic Kidney Disease 29. Sexual Dysfunction in Chronic Kidney Disease 30. Water Metabolism in Chronic Kidney Disease 32. Potassium Metabolism in Chronic Kidney Disease 33. Pathophysiology of Calcium, Phosphorus, and Magnesium in Chronic Kidney Disease 34. Acid-Base Metabolism in Chronic Kidney Disease 35. Uric Acid Metabolism and the Kidney 36. Trace Elements in Patients with Chronic Kidney Disease 37. Approach to the Patient with Chronic Glomerular Disease 38. Approach to the Patient with Hypertensive Nephrosclerosis 39. Approach to the Patient with Chronic Kidney Disease and Renovascular Disease 40. Polycystic Kidney Disease 41. Lupus Nephritis 42. Chronic Kidney Disease and Sickle Cell Disease 44. Human Immunodeficiency Virus Infection and Chronic Kidney Disease 45. Chronic Kidney Disease and Liver Disease 46. Chronic Kidney Disease and Heart Failure -- A Nephrologic Approach 48. The Interdisciplinary Chronic Kidney Disease Clinic 49. Slowing Progression of Chronic Kidney Disease 50. Nutritional Management of Patients with Chronic Kidney Disease 51. Management of Anemia in Chronic Kidney Disease 52. Management of Hypertension in Chronic Kidney Disease 53. Management of Mineral and Bone Disorders in Chronic Kidney Disease Patients 54. Albuminuria: A Target for Treatment in Diabetic and Non-Diabetic Nephropathy 55. Drug Metabolism and Chronic Kidney Disease 56. Use of Diuretics in Chronic Kidney Disease Patients 57. Non-Steroidal Anti-Inflammatory Drugs and Chronic Kidney Disease 59. Nephrolithiasis and Chronic Kidney Disease 61. Evaluation of Patients' Chronic Kidney Disease for Kidney Transplantation 64. Emerging Therapies for Chronic Kidney Disease 65. Prenatal Origins of Chronic Kidney Disease 68. Reflux Nephropathy 69. Ethnicity and Chronic Kidney Disease in Disadvantaged Populations -- An International Perspective 70. Chronic Kidney Disease in the Elderly -- Who Has it? Who Does One Treat and How are They to be Treated? 71. Pain and Chronic Kidney Disease 72. Acute Kidney Injury and Chronic Kidney Disease: A Janus-faced Syndrome 73. The Perioperative Management of the Chronic Kidney Disease Patient 74. Ethical Issues in Chronic Kidney Disease 75. Imaging the Chronic Kidney Disease Patient: Clinical Approaches, Utility and Complications