عنوان
پدید آورنده
موضوع
رده
QR360
QR360
کتابخانه
محل استقرار
شابک
شابک
3319754742
شابک
9783319754741
شابک اشتباه
3319754734
شابک اشتباه
9783319754734
عنوان و نام پديدآور
عنوان اصلي
Activation of viruses by host proteases /
نام عام مواد
[Book]
نام نخستين پديدآور
Eva Böttcher-Friebertschäuser, Wolfgang Garten, Hans Dieter Klenk, editors.
وضعیت نشر و پخش و غیره
محل نشرو پخش و غیره
Cham :
نام ناشر، پخش کننده و غيره
Springer,
تاریخ نشرو بخش و غیره
2018.
مشخصات ظاهری
نام خاص و کميت اثر
1 online resource
یادداشتهای مربوط به مندرجات
متن يادداشت
Intro; Preface; Contents; Part I: Viral Proteins Activated By Host Proteases; 1: Activation of the Hemagglutinin of Influenza Viruses; 1.1 Structural Basis for Activation of HA Fusion Potential; 1.2 Structure of HA0 Cleavage Sites; 1.3 Activating Proteases; References; 2: Proteolytic Activation of Paramyxoviruses and Pneumoviruses; 2.1 Paramyxoviruses and Pneumoviruses; 2.2 The Role of Protease Cleavage in Fusion Protein Activation; 2.3 Proteases Involved in Paramyxovirus F Protein Proteolytic Cleavage; 2.3.1 Furin and Its Role in F Protein Cleavage.
متن يادداشت
2.3.2 Extracellular Cleavage of Paramyxovirus F Proteins with Monobasic Cleavage Sites2.3.3 The Henipavirus F proteins: Intracellular Cleavage by Endosomal Proteases; 2.4 Proteases Involved in Pneumovirus F Protein Proteolytic Cleavage; 2.4.1 Respiratory Syncytial Virus F Proteins: A Novel Case of Two Proteolytic Processing Events; 2.4.2 Extracellular Cleavage of F Proteins from the Metapneumoviruses; 2.5 F protein Proteolytic Processing, Pathogenesis, and Antiviral Approaches; 2.6 Proteolytic Activation of the Hemagglutinin-ƯNeuraminidase Glycoprotein; References.
متن يادداشت
3.7.2 Peptide-Based Compounds and Small Molecules3.7.3 A Novel Cell-Based Sensor for SKI-1/S1P as a Platform for High-Throughput Drug Screening; 3.7.4 Use of the SKI-1/S1P Sensor to Predict Protease Use of Newly Emerging Arenaviruses; References; 4: Priming Time: How Cellular Proteases Arm Coronavirus Spike Proteins; 4.1 Introduction; 4.2 The Coronavirus Spike Protein: Viral Key for Entry into the Target Cell; 4.3 Proteolytic Priming of Coronavirus Spike Proteins: Basic Concepts; 4.4 Proteolytic Activation of the Spike Proteins of SARS-ƯCoV and MERS-CoV.
متن يادداشت
3: Cleavage of the Glycoprotein of Arenaviruses3.1 Arenavirus Structure, Genome Organization, and Basic Virology; 3.2 Arenavirus GP Structure and Function; 3.3 The Proprotein Convertase SKI-1/S1P Cleaves Arenavirus GPC; 3.4 The Mechanism of SKI-1/S1P Processing of Arenavirus GPC Differs from Cellular Substrates; 3.5 Optimized Recognition of Arenavirus GPC by SKI-1/S1P: Viral Advantage and Achilles' Heel; 3.6 The Processing of Reptarenavirus GPC Is Largely Unknown; 3.7 Targeting SKI-1/S1P-Mediated GPC Processing as an Anti-arenaviral Strategy; 3.7.1 Protein-Based Strategies.
متن يادداشت
4.4.1 Cathepsin L: Endosomal Activator of the Spike Protein4.4.2 Activation of the Spike Protein by Type II Transmembrane Serine Proteases at the Cell Surface; 4.4.3 Furin Can Activate Coronavirus Spike Proteins in the Constitutive Secretory Pathway of Infected Cells and During Viral Entry into Target Cells; References; 5: Proteolytic Processing of Filovirus Glycoproteins; 5.1 Introduction; 5.2 Biosynthesis and Maturation of Filovirus Glycoproteins; 5.3 The Role of GP in Host Cell Entry; 5.4 Proteases Responsible for GP Processing; References.
بدون عنوان
0
بدون عنوان
8
بدون عنوان
8
بدون عنوان
8
بدون عنوان
8
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized in three themed parts, the first part describing respective viruses and their characteristics in detail. In the second part the molecular and cellular biology of the proteases involved as well as their physiological functions will be further explored. The third part will contain a chapter on protease inhibitors that are promising tools for antiviral therapy. This book will engage scholars in virology and medical microbiology as well as researchers with an interest in enzymology and protein structure and function relationship.
یادداشتهای مربوط به سفارشات
منبع سفارش / آدرس اشتراک
Springer Nature
شماره انبار
com.springer.onix.9783319754741
ویراست دیگر از اثر در قالب دیگر رسانه
عنوان
Activation of viruses by host proteases.
شماره استاندارد بين المللي کتاب و موسيقي
9783319754734
موضوع (اسم عام یاعبارت اسمی عام)
موضوع مستند نشده
Immunology.
موضوع مستند نشده
Proteolytic enzymes.
موضوع مستند نشده
Viruses.
موضوع مستند نشده
Enzymology.
موضوع مستند نشده
Immunology.
موضوع مستند نشده
Medical microbiology & virology.
موضوع مستند نشده
Proteins.
موضوع مستند نشده
Proteolytic enzymes.
موضوع مستند نشده
SCIENCE-- Life Sciences-- Evolution.
موضوع مستند نشده
Viruses.
مقوله موضوعی
موضوع مستند نشده
MKFM
موضوع مستند نشده
MMFM
موضوع مستند نشده
SCI-- 027000
رده بندی ديویی
شماره
576
.
64
ويراست
23
رده بندی کنگره
شماره رده
QR360
نام شخص - (مسئولیت معنوی برابر )
مستند نام اشخاص تاييد نشده
Böttcher-Friebertshäuser, E.
مستند نام اشخاص تاييد نشده
Garten, Wolfgang
مستند نام اشخاص تاييد نشده
Klenk, H.-D., (Hans-Dieter),1938-
مبدا اصلی
تاريخ عمليات
20200823105945.0
قواعد فهرست نويسي ( بخش توصيفي )
pn
دسترسی و محل الکترونیکی
نام الکترونيکي
مطالعه متن کتاب اطلاعات رکورد کتابشناسی
نوع ماده
[Book]
اطلاعات دسترسی رکورد
تكميل شده
Y
