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Includes bibliographical references and index.
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Intro; Preface; Contents; Editors Biography; Part I: HSP and Stress Responses; Chapter 1: Regulation of Mammalian HSP70 Expression and Stress Response; 1.1 Introduction; 1.2 Inducible HSP70 Genes in Mammals; 1.3 HSP70 Promoter Organization and Activation; 1.4 HSF1 and its Activation by Trimerization; 1.5 Regulation of HSF1 by Posttranslational Modifications; 1.6 Factors that Coordinate with HSF1 for HSP70 Gene Expression; 1.7 Role of Other Transcription Factors in Regulation of HSP70 Expression; 1.8 Chromatin Remodeling and HSP70 Induction.
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1.9 Posttranscriptional Regulation of HSP70 Expression1.10 Regulation of HSP70 Expression at the Translation and Post-Translation Level; 1.11 Conclusions; References; Chapter 2: Heat Shock Proteins and Pesticide Stress; 2.1 Introduction; 2.2 Pesticides; 2.3 Pesticide Stress; 2.4 Heat Shock Proteins and Pesticide Stress; 2.5 Putative Mechanism of HSP Induction Under Pesticide Stress; 2.6 HSP70 as a Blocker of Pesticide Induced Cell Death; 2.7 HSP as a Biomarker of Pesticide and Other Stresses.
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3.4.5 Salt Stress3.4.6 Light Stress; 3.4.7 Flooding Stress; 3.4.8 Overlapping and Secondary Stress; 3.5 Hsp and Multistress Resistance: Connecting the Dots; 3.6 Conclusions; References; Chapter 4: Heat Shock Proteins in Stress in Teleosts; 4.1 Introduction; 4.2 Heat Shock Proteins (Hsp) in Fish; 4.3 Hsp and Thermal Stress; 4.3.1 Heat Stress Response in Fish; 4.3.2 HSP and the Heat Stress Response; 4.3.3 HSP Expression in Fishes from Naturally Heat Stressed (Hot Spring) Environments; 4.4 Hsp and Environmental Pollutatants; 4.4.1 Aquatic Environmental Pollutants.
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4.4.2 Impact of Environmental Pollutants on Aquatic Organisms4.4.3 Response of HSP in Fish against Pollution Stress; 4.4.3.1 Heavy Metals and HSP; 4.4.3.2 Arsenic; 4.4.3.3 Pesticides, Insecticides and Xenobiotics; 4.4.3.4 Salinity; 4.5 Hsp as Biomonitoring Tools for Aquatic Environmental Health Assessment; 4.6 Hsp and Immune Functions: Implications in Fish Health Management; 4.7 Conclusions; References; Chapter 5: Life in Suspended Animation: Role of Chaperone Proteins in Vertebrate and Invertebrate Stress Adaptation; 5.1 Introduction; 5.2 Heat Shock Proteins and Stress.
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The book Regulation of Heat Shock Protein Responses provides the most comprehensive review on contemporary knowledge on the regulation of HSP responses and its consequences to human diseases and disorders. Using an integrative approach to understanding the regulation of HSP responses, the contributors provide a synopsis of novel mechanisms by which HSP responses are regulated under normal physiological and pathophysiological conditions. Key basic and clinical research laboratories from major universities and academic medical hospitals around the world contribute chapters that review present research activity and importantly project the field into the future. The book is a must read for researchers, postdoctoral fellows and graduate students in the fields of Translational Medicine, Human Physiology, Biotechnology, Molecular Medicine, Infectious Diseases and Pathology.