عنوان

Myasthenia gravis and related disorders /

شابک

3319735853

شابک

9783319735856

شابک اشتباه

9783319735849

عنوان اصلي

Myasthenia gravis and related disorders /

نام عام مواد

[Book]

نام نخستين پديدآور

Henry J. Kaminski, Linda L. Kushner, editors.

وضعيت ويراست

Third edition.

محل نشرو پخش و غیره

Cham :

نام ناشر، پخش کننده و غيره

Humana Press,

تاریخ نشرو بخش و غیره

2018.

نام خاص و کميت اثر

1 online resource :

ساير جزييات

illustrations (some color)

عنوان فروست

Current clinical neurology

متن يادداشت

Includes bibliographical references and index.

متن يادداشت

Intro; Series Editor's Introduction; Preface; Contents; Contributors; 1: Neuromuscular Junction Physiology and Pathophysiology; Introduction; Structural Composition of the Neuromuscular Junction; The Presynaptic Compartment; The Synaptic Cleft; The Postsynaptic Compartment; Normal and Pathological Electrophysiology at the Neuromuscular Junction; Presynaptic Functional Events; Postsynaptic Functional Events; References; 2: Acetylcholine Receptor Structure; Introduction; Size and Shape of AChRs; Structures of AChR Subunits; Organization of Subunits in AChR Subtypes; Acetylcholine-Binding Sites

متن يادداشت

Anti-AChR Antibody MeasurementMeasurement of Muscle AChR Concentration; Muscle Histopathology; Electromyography; Acetylcholine Receptor Antibody- Specific Passive Transfer MG (AChR-PTMG); Outcome Measurements for AChR-PTMG; Experimental Humanized Mouse Model (MG-NSG); MG-NSG Protocol; Outcome Measurements for MG-NSG; Health Score; Human Anti-AChR Antibody Measurement; Measurement of Muscle AChR Concentration; Animal Models of MuSK Myasthenia; Active Immunization Models of MuSK Myasthenia (MuSK-EAMG); Passive IgG Transfer Mouse Model of MuSK Myasthenia (MuSK-PTMG)

متن يادداشت

Cation Channel and Its GateAntigenic Structure and the Main Immunogenic Region (MIR); Induction of the Autoimmune Response to AChRs in MG; Autoimmune Mechanisms Which Impair Neuromuscular Transmission in MG and EAMG; Effects of AChR Mutations in Congenital Myasthenic Syndromes; Neuronal AChR Subtypes and Functional Roles; Autoimmune Impairment of Neuronal AChRs; Effects of Human Neuronal AChR Mutations; References; 3: Immunopathogenesis of Myasthenia Gravis; Introduction; Heterogeneity of Myasthenia Gravis; Targets of the Autoimmune Response; Typical Features of MG Subtypes; AChR-MG

متن يادداشت

MuSK-MG PatientsLRP4-MG Patients; Other Targets; Thymus Pathology; Thymomas; Thymic Follicular Hyperplasia; Effects of Thymectomy; Dysregulation of the Immune System; The Role of B Cells; Treg and Th17 Cells; Follicular Helper T Cells; What Are the Causes of MG?; Contribution of Genetics; Role of the MicroRNA; Triggering Factors; References; 4: Animal Models of Myasthenia Gravis for Preclinical Evaluation; Anti-AChR-Experimental Autoimmune MG (AChR-EAMG); Classical EAMG Mouse Model; Classical AChR-EAMG Rat Model: Induction; Outcome Measurements for AChR-­EAMG Models; Health Score

متن يادداشت

Outcome Measurements for Rodent Models of MuSK MyastheniaAnimal Care; Rigor of Study Design; References; 5: Epidemiology and Genetics of Myasthenia Gravis; Introduction; Epidemiology of MG; Epidemiology of Antigen Subtypes; AChR Antibody-Positive MG (AChR-MG); MuSK Antibody-Positive MG; LRP4 Antibody-Positive MG; Triple-Seronegative MG (AChR-/MuSK-/LRP4-Antibody Negative); Epidemiology of Clinical Subtypes of MG; Ocular MG; Generalized MG; Thymoma-Associated MG; Treatment-Resistant Ophthalmoplegia; Genetics of Myasthenia Gravis; Non-HLA Genes

بدون عنوان

0

بدون عنوان

8

بدون عنوان

8

بدون عنوان

8

بدون عنوان

8

متن يادداشت

The third edition of this important, gold-standard title outlines a range of significant advances in the study and understanding of myasthenia gravis. The overarching goal of this new edition is identical to the first and second -- to provide the clinician and the scientist with a common resource for understanding the profound achievements in the clinical, translational, and basic sciences of neuromuscular transmission disorders. In addition to several new authors and an extensive update of all chapters, this third edition includes summaries of pre-clinical research standards for autoimmune MG, along with a broad summary of MG clinical trial performance. The now greater understanding of the clinical presentation of MuSK-related MG and identification of potential new autoantigens, including LRP-4, is discussed. The development of treatment guidelines by groups in Japan, the United Kingdom, Germany, and an international consortium is also outlined. Myasthenia Gravis and Related Disorders, Third Edition, is an invaluable resource for meeting the many and varied needs of clinicians who treat patients with myasthenia gravis.

منبع سفارش / آدرس اشتراک

Springer Nature

شماره انبار

com.springer.onix.9783319735856

موضوع مستند نشده

Myasthenia gravis-- Pathophysiology.

موضوع مستند نشده

Myoneural junction.

موضوع مستند نشده

Neuromuscular diseases-- Pathophysiology.

موضوع مستند نشده

HEALTH & FITNESS-- Diseases-- General.

موضوع مستند نشده

Immunology.

موضوع مستند نشده

MEDICAL-- Clinical Medicine.

موضوع مستند نشده

MEDICAL-- Diseases.

موضوع مستند نشده

MEDICAL-- Evidence-Based Medicine.

موضوع مستند نشده

MEDICAL-- Internal Medicine.

موضوع مستند نشده

Myoneural junction.

موضوع مستند نشده

Neurology & clinical neurophysiology.

موضوع مستند نشده

Neurosciences.

موضوع مستند نشده

Respiratory medicine.

موضوع مستند نشده

HEA-- 039000

موضوع مستند نشده

MED-- 014000

موضوع مستند نشده

MED-- 022000

موضوع مستند نشده

MED-- 045000

موضوع مستند نشده

MED-- 112000

شماره

ويراست

شماره رده

مستند نام اشخاص تاييد نشده

Kaminski, Henry J.

مستند نام اشخاص تاييد نشده

Kushner, Linda L.

تاريخ عمليات

20200823104313.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y