عنوان

Life histories of genetic disease :

شابک

1421420759

شابک

9781421420752

شابک اشتباه

1421420740

شابک اشتباه

9781421420745

عنوان اصلي

Life histories of genetic disease :

نام عام مواد

[Book]

ساير اطلاعات عنواني

patterns and prevention in postwar medical genetics /

نام نخستين پديدآور

Andrew J. Hogan.

محل نشرو پخش و غیره

Baltimore :

نام ناشر، پخش کننده و غيره

Johns Hopkins University Press,

تاریخ نشرو بخش و غیره

2016.

نام خاص و کميت اثر

1 online resource

متن يادداشت

Includes bibliographical references and index.

متن يادداشت

Introduction : pursuing a better birth -- Genetics detectives -- Chromosomal cartography -- The genome's morbid anatomy -- Seeing with molecules -- Institutionalized disorders -- Getting the whole picture -- Epilogue : the genomic gaze.

بدون عنوان

0

متن يادداشت

Medical geneticists began mapping the chromosomal infrastructure piece by piece in the 1970s by focusing on what was known about individual genetic disorders. Five decades later, their infrastructure had become an edifice for prevention, allowing today's expecting parents to choose to test prenatally for hundreds of disease-specific mutations using powerful genetic testing platforms. In Life Histories of Genetic Disease, Andrew J. Hogan explores how various diseases were "made genetic" after 1960, with the long-term aim of treating and curing them using gene therapy. In the process, he explains, these disorders were located in the human genome and became targets for prenatal prevention, while the ongoing promise of gene therapy remained on the distant horizon. In narrating the history of research that contributed to diagnostic genetic medicine, Hogan describes the expanding scope of prenatal diagnosis and prevention. He draws on case studies of Prader-Willi, fragile X, DiGeorge, and velo-cardio-facial syndromes to illustrate that almost all testing in medical genetics is inseparable from the larger-and increasingly "big data"--Oriented-aims of biomedical research.

عنوان

Life histories of genetic disease.

شماره استاندارد بين المللي کتاب و موسيقي

9781421420745

موضوع مستند نشده

Genetic disorders-- Diagnosis.

موضوع مستند نشده

Medical genetics-- Moral and ethical aspects.

موضوع مستند نشده

Medical genetics.

موضوع مستند نشده

Genetic Diseases, Inborn-- prevention & control.

موضوع مستند نشده

Genetics, Medical-- history.

موضوع مستند نشده

History, 20th Century.

موضوع مستند نشده

History, 21st Century.

موضوع مستند نشده

Genetic disorders-- Diagnosis.

موضوع مستند نشده

HEALTH & FITNESS-- Diseases-- General.

موضوع مستند نشده

MEDICAL-- Clinical Medicine.

موضوع مستند نشده

MEDICAL-- Diseases.

موضوع مستند نشده

MEDICAL-- Evidence-Based Medicine.

موضوع مستند نشده

Medical genetics-- Moral and ethical aspects.

موضوع مستند نشده

Medical genetics.

موضوع مستند نشده

MEDICAL-- Internal Medicine.

موضوع مستند نشده

HEA-- 039000

موضوع مستند نشده

MED-- 014000

موضوع مستند نشده

MED-- 022000

موضوع مستند نشده

MED-- 045000

موضوع مستند نشده

MED-- 112000

شماره

ويراست

شماره رده

شماره رده

مستند نام اشخاص تاييد نشده

Hogan, Andrew J.

تاريخ عمليات

20200822182346.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y