عنوان

Clinical Application of Radiolabelled Platelets

شابک

9400905815

شابک

9789400905818

شماره

b592408

عنوان اصلي

Clinical Application of Radiolabelled Platelets

نام عام مواد

[Book]

نام نخستين پديدآور

edited by Ch. Kessler, M. R. Hardeman, H. Henningsen, J.-N. Petrovici.

محل نشرو پخش و غیره

Dordrecht Springer Netherlands

تاریخ نشرو بخش و غیره

1990

نام خاص و کميت اثر

(301 p).

عنوان فروست

Developments in Nuclear Medicine, 17

متن يادداشت

AIMS OF THE COLOGNE-SYMPOSIUM ON RADIOLABELLED PLATELETS In 1976, M. Thakur et al (1) were the first to publish a paper concerning the in vivo thrombus detection with 111- In-labelled platelets. Previous attempts at scintigraphic thrombus localisation had been disappointing because of the unspecific binding of a number of the isotopes used, as well as the poor labelling efficiency or an insufficient low gamma-emitting property. Because of its physical characteristics (2.8 days half-life, 94% gamma emission) 111 Indium turned out to be the best isotope for platelet kinetic studies as well as for the measurement of platelet incorporation by Thrombi to be used up until now. The lipophile complexes of Ill-In (8-hydroxyquinoline, acetylacetone, tropolone) diffuse passively into the platelets without altering the function or the life span of the platelets. This advantage has let to an increase in the clinical applications of 1211-In labelled platelets. Today, radiolabelled platelets are used for thrombus detection in several different medical areas such as cardiology, nephrology. angiology or neurology. Even though many scientists and hospital doctors now routinely use radiolabelled platelet as a diagnostic tool, there is as yet not a standardized labelling method. In addition to this, there are neither standardized image procedures for the different clinical applications nor an agreement about specificity and sensitivity of the method. In 1983, a symposium on Radiolabelled Cellular Blood Elements was organized by M.Thakur, M.R.Hardeman and M.D.

موضوع مستند نشده

Hematology.

موضوع مستند نشده

Internal Medicine.

موضوع مستند نشده

Nuclear Medicine.

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

edited by Ch. Kessler, M. R. Hardeman, H. Henningsen, J.-N. Petrovici.

مستند نام اشخاص تاييد نشده

Ch Kessler

مستند نام اشخاص تاييد نشده

H Henningsen

مستند نام اشخاص تاييد نشده

J -N Petrovici

مستند نام اشخاص تاييد نشده

M R Hardeman

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y