عنوان

Carcinogenicity :

شابک

3642613640

شابک

9783642613647

شماره

b571762

عنوان اصلي

Carcinogenicity :

نام عام مواد

[Book]

ساير اطلاعات عنواني

the Design, Analysis, and Interpretation of Long-Term Animal Studies

نام نخستين پديدآور

edited by Harold C. Grice, Joseph L. Ciminera.

محل نشرو پخش و غیره

Berlin, Heidelberg

نام ناشر، پخش کننده و غيره

Springer Berlin Heidelberg

تاریخ نشرو بخش و غیره

1988

نام خاص و کميت اثر

(xix, 279 pages)

عنوان فروست

ILSI monograph.

متن يادداشت

Biological and Statistical Assumptions in Analyses of the Bioassay --; Value of Historical Control Data --; Dose Selection --; Criteria for Classifying Neoplasms and Use of Data on Nonneoplastic Lesions --; Observer Bias in Histopathological Examinations --; Modulating Factors: Challenges to Experimental Design --; Options for Aggregation of Incidence Data --; Reevaluation of Pathology Data in Regulatory Decision Process --; Interpretation of Multiple Studies and Design of Repeat Studies --; Issues in Decision Making --; Index.

متن يادداشت

Critical issues in the design, evaluation and interpretation of long-term animal carcinogenicity studies are addressed in this volume. The presentations are by top pathologists, toxicologists and statisticians in the USA, Canada and Europe, representing industry, academia and regulatory agencies. The discussions involve controversial as well as conventional issues and are presented from statistical and biological or toxicological perspectives. Although more work has been done and published on long-term animal carcinogenicity studies than in any other phase of chemical or drug safety assessment, many issues still remain unresolved. Some solutions have been proposed, but in many instances they have not proven to be completely remedial. This volume continues important discussion of these issues and proposed solutions, and should be of interest to scientists engaged in long-term animal carcinogenicity testing.

عنوان اصلي به زبان ديگر

Proceedings of the Interdisciplinary Discussion Group on Carcinogenicity Studies Held in Chapel Hill, NC, June 23-26, 1986

موضوع مستند نشده

Medicine.

موضوع مستند نشده

Oncology.

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

edited by Harold C. Grice, Joseph L. Ciminera.

مستند نام اشخاص تاييد نشده

Harold C Grice

مستند نام اشخاص تاييد نشده

Joseph L Ciminera

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y