عنوان

Inhalation Toxicology :

شابک

3642613551

شابک

9783642613555

شماره

b571759

عنوان اصلي

Inhalation Toxicology :

نام عام مواد

[Book]

ساير اطلاعات عنواني

the Design and Interpretation of Inhalation Studies and Their Use in Risk Assessment

نام نخستين پديدآور

edited by Donald L. Dungworth, Georg Kimmerle, James Lewkowski, Roger O. McClellan, Werner Stöber.

محل نشرو پخش و غیره

Berlin, Heidelberg

نام ناشر، پخش کننده و غيره

Springer Berlin Heidelberg

تاریخ نشرو بخش و غیره

1988

نام خاص و کميت اثر

(xiii, 318 pages 114 illustrations)

عنوان فروست

ILSI monographs.

متن يادداشت

I. Approaches to Assessing the Toxicity of Airborne Toxicants --; 1. Standard-Setting as an Integrative Exercise: Alchemy, Juggling, or Science? --; 2. Species Differences in Inhalation Toxicology: Variations in Exposure-Dose Relationships and Macrophage Function --; 3. Cell Populations of the Respiratory System: Interspecies Diversity in Composition, Distribution, and Morphology --; 4. Comparative Metabolic Basis for the Disposition and Toxic Effects of Inhaled Materials --; II. Methodological Issues in Designing and Conducting Studies with Laboratory Animals --; 5. Exposure Facilities and Aerosol Generation and Characterization for Inhalation Experiments --; 6. Different Methods Used in Acute and Subchronic Inhalation Studies of Potential Lung Irritants, with Particular Attention to Lung Function Measurements --; 7. Chronic Inhalation Toxicity Studies: Protocols and Pitfalls --; 8. Carcinogenicity Protocols --; III. Interpretation of Toxicokinetic Studies with Airborne Toxicants --; 9. Interspecies Dosimetry of Reactive Gases --; 10. Behavior of Inspired Aerosol Boli in Humans --; 11. Respiratory Tract Clearance of Particles and Substances Dissociated from Particles --; IV. Interpretation of Results Using Laboratory Animals --; 12. Interpretation of Early Lesions in the Mouse Lung: Fibrogenesis and Tbmorigenesis --; 13. Relevance to Humans of Experimentally Induced Pulmonary Tumors in Rats and Hamsters --; 14. Experimentally Induced Emphysema and Long-Term Nitrogen Dioxide Inhalation --; 15. Comparison of Respiratory Function Responses of Laboratory Animals and Humans --; V. Risk Assessment of Airborne Toxicants --; 16. Population Studies in Risk Assessment: Strengths and Weaknesses --; 17. Human Clinical Exposure Studies: Body Box or Pandora's Box? --; 18. Occupational Exposure Standards in Europe: History, Present Status, and Future Trends --; 19. Current Approaches for Determining Workplace Exposure Limits in the USA.

متن يادداشت

The International Life Sciences Institute (ILSI), a nonprofit, public foundation, was established in 1978 to advance the sciences of nutrition, toxicology, and food safety. ILSI promotes the resolution of health and safety issues in these areas by sponsoring research, conferences, publications, and educational programs. Through ILSI's programs, scientists from government, academia, and industry unite their efforts to resolve issues of critical importance to the public. As part of its commitment to understanding and resolving health and safety issues, ILSI is pleased to sponsor this series of monographs that consolidates new scientific knowledge, defines research needs, and provides a background for the effective application of scientific advances in toxicology and food safety. Alex Malaspina President International Life Sciences Institute Contents Series Foreword ... ... ... ... v Contributors ... ... ... ... . xi Part I. Approaches to Assessing the Toxicity of Airborne Toxicants Chapter 1. Standard-Setting as an Integrative Exercise: Alchemy, Juggling, or Science? ... ... . 1 D. v. Bates Chapter 2. Species Differences in Inhalation Toxicology: Variations in Exposure-Dose Relationships and Macrophage Function. ... ... ... 11 J.D. Brain Chapter 3. Cell Populations of the Respiratory System: Interspecies Diversity in Composition, Distribution, and Morphology ... ... 25 e. G. Plopper, A. Mir, J. St. George, N. Tyler, A. Mariassy, D. Wilson, S. Nishio, D. Cranz, J. Heidsiek, and D. Hyde Chapter 4. Comparative Metabolic Basis for the Disposition and Toxic Effects of Inhaled Materials ... ... 41 A.R. Dahl Part II. Methodological Issues in Designing and Conducting Studies with Laboratory Animals Chapter 5. Exposure Facilities and Aerosol Generation and Characterization for Inhalation Experiments. ...

موضوع مستند نشده

Medicine.

موضوع مستند نشده

Pathology.

موضوع مستند نشده

Pneumology.

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

edited by Donald L. Dungworth, Georg Kimmerle, James Lewkowski, Roger O. McClellan, Werner Stöber.

مستند نام اشخاص تاييد نشده

Donald L Dungworth

مستند نام اشخاص تاييد نشده

Georg Kimmerle

مستند نام اشخاص تاييد نشده

James Lewkowski

مستند نام اشخاص تاييد نشده

Roger O McClellan

مستند نام اشخاص تاييد نشده

Werner Stöber

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y