عنوان

The role of microenvironment in axonal regeneration :

شابک

3642607810

شابک

9783642607813

شماره

b571611

عنوان اصلي

The role of microenvironment in axonal regeneration :

نام عام مواد

[Book]

ساير اطلاعات عنواني

influences of lesion-induced changes and glial implants on the regeneration of the postcommissural fornix

نام نخستين پديدآور

Christine C. Stichel-Gunkel.

محل نشرو پخش و غیره

Berlin ; New York

نام ناشر، پخش کننده و غيره

Springer

تاریخ نشرو بخش و غیره

©1997.

نام خاص و کميت اثر

(viii, 81 pages) : illustrations

عنوان فروست

Advances in anatomy, embryology, and cell biology, v. 137.

متن يادداشت

Introduction; - Axonal regeneration in the adult mammalian CNS --; Aims of the study --; Materials and methods --; Cell culture techniques --; Surgical procedures --; Tissue procedures --; Tissue processing --; Histological methods --; Immunohistochemical methods --; In situ-Hybridisation --; Quantitative analysis --; Results --; Unlesioned postcommissural fornix --; Sequence of cellular and molecular reactions following axonal transection --; Glial cell implantations --; Discussion --; Role of lesion-induced cellular and molecular changes in degeneration and regeneration --; The impact of glial implants on axonal regeneration --; Summary and perspectives --; References; - Subject Index.

متن يادداشت

Since the pioneering studies of Ramon y Cajal the inability of lesioned adult CNS axons to regenerate has been well established. During the past years advancements in molecular, cellular and biochemical knowledge have provided new insights into the extrinsic mechanims underlying regeneration failure. The rapid progress in this field has already led to the development of new concepts for therapeutic manipulations. This book provides a comprehensive overview of structural and molecular changes induced by an invasive CNS lesion and their involvements in regeneration processes. Moreover, it demonstrates the strong growth-promoting actitivies of implanted glial cells. The data is discussed in relation to current knowledge on the mechanisms of axonal degeneration and regeneration and in terms of their relevance for the development of novel therapeutic strategies.

موضوع مستند نشده

Axons.

موضوع مستند نشده

Nervous system -- Regeneration.

موضوع مستند نشده

Neuroglia.

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

Christine C. Stichel-Gunkel.

مستند نام اشخاص تاييد نشده

Christine C Stichel-Gunkel

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y