عنوان

General Principles and Etiology

شابک

1468428500

شابک

1468428527

شابک

9781468428506

شابک

9781468428520

شماره

b554216

عنوان اصلي

General Principles and Etiology

نام عام مواد

[Book]

نام نخستين پديدآور

edited by James G. Wilson, F. Clarke Fraser.

محل نشرو پخش و غیره

Boston, MA

نام ناشر، پخش کننده و غيره

Springer US : Imprint : Springer

تاریخ نشرو بخش و غیره

1977

نام خاص و کميت اثر

(XI, 476 pages)

متن يادداشت

Section I: Introduction --;1 History of Teratology --;2 Current Status of Teratology --;General Principles and Mechanisms Derived From Animal Studies --;3 Relation of Animal Studies to the Problem in Man --;Section II: Causes of Maldevelopment --;4 Action of Mutagenic Agents --;5 Radiations and Other Physical Agents --;6 Infectious Diseases --;7 Nutritional Deficiencies and Excesses --;8 Embryotoxicity of Drugs in Man --;9 Environmental Chemicals --;10 Maternal Metabolic and Endocrine Imbalances --;11 Atmospheric Gases --;Variations in Concentration and Some Common Pollutants --;12 Extremes of Temperature --;13 Interactions and Multiple Causes.

متن يادداشت

In less than 40 years teratology has grown from a little known discipline concerned with studies on the effects of a few physical and chemical stresses on developing fish, amphibians, and birds, to a discipline embracing a vast accumulation of literature on experimental studies in many animal forms and the results of intensive scrutiny of human development under varied conditions, as well. Emphasis has shifted from preoccupation with descrip tions of anatomical defects to concern about subtle and interacting causative factors, to searches for the early reactions to these at the cellular and subcellu lar levels, and to identification of abnormality in the chemical, the functional, and the ultrastructural realms. These changes in orientation have quite naturally made necessary the recruitment of concepts, methods, and expertise from other disciplines. Hence the foundations of teratology, which once were largely morphological, have extended into genetics, biochemistry, molecular biology, reproductive physiology, epidemiology, and several aspects of veteri nary and clinical medicine. It is not surprising that a student or new investigator approaching the field of teratology may feel some dismay when confronted with the confusing array of cross-disciplinary concepts and principles it encompasses today. One of the aims of this work is to introduce what the editors believe is a logical thread of continuity into a field that may be regarded by some as a welter of disordered information.

موضوع مستند نشده

Science (General)

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

edited by James G. Wilson, F. Clarke Fraser.

مستند نام اشخاص تاييد نشده

F Clarke Fraser

مستند نام اشخاص تاييد نشده

James G Wilson

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y