عنوان

Gene therapy for HIV :

شابک

1493904345 (electronic bk.)

شابک

9781493904341 (electronic bk.)

شابک اشتباه

1493904337

شابک اشتباه

9781493904334

شماره

dltt

عنوان اصلي

Gene therapy for HIV :

نام عام مواد

[Book]

ساير اطلاعات عنواني

from inception to a possible cure /

نام نخستين پديدآور

Gerhard Bauer, Joseph S. Anderson

نام خاص و کميت اثر

1 online resource.

عنوان فروست

SpringerBriefs in Biochemistry and Molecular Biology

متن يادداشت

Includes bibliographical references

متن يادداشت

This Brief describes the concept and realization of gene therapy for HIV from the unique historic perspective and insight of two pioneers of the clinical applications of stem cell gene therapy for HIV. Gerhard Bauer applied ribozyme-anti-HIV and other vectors to manufacture clinical grade, HIV-resistant hematopoietic stem cells for the first patients that received stem cell gene therapy for HIV, including the first child in the world and the first fully marrow-ablated HIV infected patient. Joseph Anderson developed the most recent and most potent combination anti-HIV lentiviral vectors and pluripotent stem cell applications for HIV gene therapy and tested these in the appropriate in vitro and vivo models, paving the way for novel HIV gene therapy approaches to possibly cure patients. In Gene Therapy for HIV, Bauer and Anderson discuss the unique aspects of this therapy, including its limitations and proper safety precautions and outline a path for a possible functional cure for HIV using stem cell gene therapy based on a cure already achieved with a bone marrow stem cell transplantation performed in Germany using donor stem cells with a naturally arising CCR5 mutation. In addition, the Brief provides a thorough and methodical explanation of the basics of gene therapy, gene therapy vector development, in vitro and in vivo models for HIV gene therapy and clinical applications of HIV gene therapy, including Good Manufacturing Practices

عنوان

Gene therapy for hiv

شماره استاندارد بين المللي کتاب و موسيقي

1493904337

موضوع مستند نشده

AIDS (Disease)-- Gene therapy.

موضوع مستند نشده

HIV infections-- Gene therapy.

موضوع مستند نشده

HEA-- 039000

موضوع مستند نشده

MED-- 014000

موضوع مستند نشده

MED-- 022000

موضوع مستند نشده

MED-- 045000

موضوع مستند نشده

MED-- 112000

شماره

ويراست

شماره رده

مستند نام اشخاص تاييد نشده

Bauer, Gerhard, (Assistant professor)

مستند نام اشخاص تاييد نشده

Anderson, Joseph S.

مستند نام تنالگان تاييد نشده

Ohio Library and Information Network.

تاريخ عمليات

20201222074513.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

کد کاربرگه

270410

تكميل شده

Y