Research and development of opioid-related ligands /
نام عام مواد
[Book]
نام نخستين پديدآور
Mei-Chuan Ko, editor, Wake Forest University, Winston-Salem, North Carolina, United States, Stephen M. Husbands, editor, University of Bath, Bath, United Kingdom
مشخصات ظاهری
نام خاص و کميت اثر
xi, 429 pages, 2 pages of plates :
ساير جزييات
illustrations (some color) ;
ابعاد
24 cm
فروست
عنوان فروست
ACS symposium series ;
مشخصه جلد
1131
یادداشتهای مربوط به کتابنامه ، واژه نامه و نمایه های داخل اثر
متن يادداشت
Includes bibliographical references and indexes
یادداشتهای مربوط به مندرجات
متن يادداشت
Commentaries: Commentary on the current status of clinically used analgesics / Thomas M. Dodds. Commentary on the current state of opioid-related research / John W. Lewis -- Clinical studies of pain and opioids: The clinical importance of conditioning pain modulation : a review and clinical implications / Mellar P. Davis.- Treatment of pain and opioid abuse / Shanthi Mogali and Sandra D. Comer. Treatment of opioid dependence / Andrew J. Saxon. Buprenorphine in the treatment of neuropathic pain / Guy H. Hans -- Development of new ligands: Buprenorphine and related orvinols / Stephen M. Husbands. Structure-activity relationships of nociceptin receptor (NOP) ligands and the design of bifunctional NOP/Mu opioid receptor-targeted ligands / Nurulain T. Zaveri, Dennis Yasuda, Blair V. Journigan, Pankaj R. Daga, Faming Jiang, and Cris Olsen. Mu, delta and kappa opioid agonist effects in novel assays of pain-depressed behavior / S. Stevens Negus and Ahmad A. Altarifi. Functionally biased agonism of mu and kappa opioid receptors / Donald J. Kyle -- Pharmacology of classical opioid receptors: Peripherally restricted opioid analgesics / Patrick J. Little. The delta opioid receptor / A.M. Symons-Liguori and T.W. Vanderah. Kappa opioids : problems and opportunities in analgesia / Edurado R. Butelman and Mary Jeanne Kreek. Mixed mu/kappa opioid agonists / Jean M. Bidlack and Brian I. Knapp -- Pharmacology of NOP receptors: Medicinal chemistry, pharmacology, and biological actions of peptide ligands selective for the nociceptin/orphanin FQ receptor / Girolamo Calo' and Remo Guerrini. A review of the NOP (ORL-1)-nociceptin/orphanin FQ system covering receptor structure, distribution, role in analgesia and reward and interactions with other receptors / Garth T. Whiteside and Donald J. Kyle. Pharmacology of mixed NOP/Mu ligands / Lawerence Toll, Taline V. Khroyan, Willma E. Polgar, Stephen M. Husbands, and Nurulain T. Zaveri. Pharmacological investigation of NOP-related ligands as analgesics without abuse liability / Devki Sukhtankar and Mei-Chuan Ko