Principles of gene manipulation and genomics /S.B. Primrose and R.M. Twyman.
General Material Designation
[Book]
EDITION STATEMENT
Edition Statement
7th ed.
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Malden, MA ;Oxford :
Name of Publisher, Distributor, etc.
: Blackwell Pub
Date of Publication, Distribution, etc.
, 2006.
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
xxii, 644 p.
Other Physical Details
:ill.
Dimensions
;28 cm.
GENERAL NOTES
Text of Note
English
Text of Note
Rev. ed. of: Principles of gene manipulation. 6th ed. 2001 and Principles of genome analysis and genomics / Sandy B. Primrose, Richard M. Twyman. 3rd ed. 2003.
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references (p. [547]-626) and index.
CONTENTS NOTE
Text of Note
Gene manipulation in the post-genomics era -- Basic techniques -- Cutting and joining DNA molecules -- Basic biology of plasmid and phage vectors -- Cosmids, phasmids, and other advanced vectors -- Gene cloning strategies -- Sequencing genes and short stretches of DNA -- Changing genes : site-directed mutagenesis and protein engineering -- Bioinformatics -- Cloning in bacteria other than Escherichia coli -- Cloning in Saccharomyces cerevisiaea and other fungi -- Gene transfer to animal cells -- Genetic manipulation of animals -- Gene transfer to plants -- Advanced transgenic technology -- The organization and structure of genomes -- Mapping and sequencing genomes -- Comparative genomics -- Large-scale mutagenesis and interference -- Analysis of the transcriptome -- Proteomics I : expression analysis and characterization of proteins -- Proteomics II : analysis of protein structures -- Proteomics III : protein interactions -- Metabolomics and global biochemical networks -- Applications of genomics : understanding the basis of polygenic disorders and identifying quantitative trait loci -- Applications of recombinant DNA technology.