/ edited by Christian Schudt, Gordon Dent and Klaus F. Rabe
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
San Diego
Name of Publisher, Distributor, etc.
: Academic Press,
Date of Publication, Distribution, etc.
, 1996.
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
1 online resource.
SERIES
Series Title
(The Handbook of immunopharmacology. Drugs)
GENERAL NOTES
Text of Note
Description based on print version record.
NOTES PERTAINING TO PUBLICATION, DISTRIBUTION, ETC.
Text of Note
e
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index.
CONTENTS NOTE
Text of Note
Identification and quantification of PDE isoenzymes and subtypes by molecular biological methods -- Analysis of PDE isoenzyme profiles in cells and tissues by pharmacological methods -- Effects of theophylline and non-selectiveanthine derivatives on PDE isoenzymes nad cellular function -- Ca2+/calmodulin-dependent cyclic nucleotide phosphodiesterase (PDEI) -- EHNA as an inhibitor of PDE2; a pharmacological and biochemical study in cardiac myocytes -- cGMP-inhibited phosphodiesterases (PDE3) -- Interaction of PDE4 inhibitors with enzymes and cell functions -- Inhibition of phosphodiesterase isoenzymes and cell function by selective PDE5 inhibitors -- Design and synthesis ofanthines and cyclic GMP analogues as potent inhibitors of PDE5 -- Enzymatic and functional aspects of dual-selective PDE3/4 inhibitors -- An isoform-selective inhibitor of cyclic AMP-specific phosphodiesterase (PDE4) with anti-inflammatory properties -- Characterization of different states of PDE4 by rolipram and RP 73041 -- Molecular aspects of inhibitor interaction with PDE4.