Target family-directed masterkeyes in chemogenomics /Gehard Muller --Drug discovery from side effects /Hugo Kubinyi --The value of chemical genetics in drug discovery /Keith Russell and William F. Michne --Structural aspects of binding site similarity: a 3D upgrade for chemogenomics /Andreas Bergner and Judith Gunther --The contribution of molecular informatics to chemogenomics: knowledge-based discovery of biological targets and chemical lead compounds /Edgar Jacoby, Ansgar Schuffenhauer, and Pierre Acklin --Chemical kinomics /Bert M. Klebl, Henrik Daub, and Gyorgy Keri --Structural aspects of kinases and their inhibitors /Rogier Buijsman --A chemical genomics approach for ion channel modulators /Karl-Heinz Baringhaus and Gerhard Hessler -- Phosphodiesterase inhibitors: a chemogenomic view /Martin Hendrix and Christopher Kallus --Proteochemometrics: a tool for modeling the molecular interaction space /Jarl E.S. Wikberg, Maris Lapinsch, and Peteris Prusis --Some principles related to chemogenomics in compound library and template design for GPCRs /Thomas R. Webb --Computational filters in lead generation: targeting drug-like chemotypes /Wolfgang Guba and Olivier Roche --Navigation in chemical space: ligand-based design of focused compound libraries /Gisbert Schneider and Petra Schneider --Natural product-derived compound libraries and protein structure similarity as guiding principles for the discovery of drug candidates /Marcus A. Koch and Herbert Waldmann --Combinatorial chemistry in the age of chemical genomics /Reni Joseph and Prabhat Arya.
NATIONAL BIBLIOGRAPHY NUMBER
Number
02BL0000000012307
Number
02BL0000000012295
LANGUAGE OF THE ITEM
.Language of Text, Soundtrack etc
انگلیسی
.Language of Text, Soundtrack etc
انگلیسی
TITLE AND STATEMENT OF RESPONSIBILITY
Title Proper
Chemogenomics in drug discovery
First Statement of Responsibility
edited by Hugo Kubinyi and Gerhard Muller
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Weinheim
Name of Publisher, Distributor, etc.
Wiley-VCH
Date of Publication, Distribution, etc.
,c2004
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
xxiv, 463 p. ill. )some col.( 25 cm.
SERIES
Series Title
Methods and principles in medicinal chemistry ;v. 22
NOTES PERTAINING TO TITLE AND STATEMENT OF RESPONSIBILITY