INTERNATIONAL STANDARD BOOK NUMBER
(Number (ISBN
9781441978622
NATIONAL BIBLIOGRAPHY NUMBER
Country Code
IR
Number
EN-59769
LANGUAGE OF THE ITEM
.Language of Text, Soundtrack etc
انگلیسی
COUNTRY OF PUBLICATION OR PRODUCTlON
Country of publication
IR
TITLE AND STATEMENT OF RESPONSIBILITY
Title Proper
Characterization of Protein Therapeutics using Mass Spectrometr
General Material Designation
[Book]
First Statement of Responsibility
/ edited by Guodong Chen
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Boston, MA
Name of Publisher, Distributor, etc.
: Springer US :Imprint: Springer,
Date of Publication, Distribution, etc.
, 2013.
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
X, 404 p. 148 illus., 38 illus. in color., online resource.
NOTES PERTAINING TO PUBLICATION, DISTRIBUTION, ETC.
Text of Note
Electronic
CONTENTS NOTE
Text of Note
Protein therapeuticsa?? high efficacy, safety, and ability to treat life-threatening diseases such as cancer, inflammation and genetic disorders have revolutionized modern medicine. In 2012, 200 companies competed in this $90 billion year industry. ?a In Characterization of Protein Therapeutics using Mass Spectrometry, expert contributors from academia and industry highlight current approaches and future trends. The book discusses mass spectrometry techniques as related to the analysis of protein therapeutics, structural identification strategies and quantitative approaches. The book also covers various studies involving characterization of process related protein drug impurities/degradants, metabolites, PTMs and?a higher order structures of protein therapeutics. ?a General practitioners in pharmaceutical research, specialists in analytical sciences, and graduate students studying mass spectrometry and pharmaceutical sciences will find this book useful because of ?athe ?astep-by-step approaches and new strategies to solve challenging problems related to protein therapeutics research and development.
Text of Note
Characterization of Protein Therapeutics by Mass Spectrometry: Recent Developments and Future Directions -- The Use of Mass Spectrometry to Characterize the Metabolism of Peptide Therapeutics -- Quantitative Analysis of Biologics Using Mass Spectrometry -- Maximizing Structural Information from Whole Protein Tandem Mass Spectrometry -- Disulfide Linkages of an Albumin Fusion Protein -- Detailed Structural Characterization of Monoclonal Antibodies -- Application of Protein Mass Spectrometry in Impurity and Degradant Characterization -- Mass Spectrometry Methods to Analyze Higher Order Structure of Protein Therapeutics by Chemical Footprinting -- Aglycosylations Alters Protein Conformation in Antibodies Engineered with Specific Effector Functions Using HDX-MS -- Characterizing Biotherapeutic Protein 3D Structures by Electrospray Ion-Mobility Mass Spectrometry -- Oxford University, Characterization of Assemblies of Proteins by Mass Spectrometry.
TOPICAL NAME USED AS SUBJECT
Chemistry
Human genetics
Pharmaceutical technology
Mass spectrometry
Biotechnology
Biochemistry
Surfaces (Physics)
Electronic books
LIBRARY OF CONGRESS CLASSIFICATION
Class number
E-BOOK
PERSONAL NAME - PRIMARY RESPONSIBILITY
Chen, Guodong.
PERSONAL NAME - SECONDARY RESPONSIBILITY
SpringerLink (Online service)
ORIGINATING SOURCE
Country
ایران
ELECTRONIC LOCATION AND ACCESS
Host name
9781441978615.pdf
Access number
عادی
Compression information
عادی
Date and Hour of Consultation and Access
9781441978615.pdf
Electronic Format Type
متن
old catalog
e
BL
1
a
Y
