INTERNATIONAL STANDARD BOOK NUMBER
(Number (ISBN
9781627032995
NATIONAL BIBLIOGRAPHY NUMBER
Country Code
IR
Number
EN-59762
LANGUAGE OF THE ITEM
.Language of Text, Soundtrack etc
انگلیسی
COUNTRY OF PUBLICATION OR PRODUCTlON
Country of publication
IR
TITLE AND STATEMENT OF RESPONSIBILITY
Title Proper
Systems Metabolic Engineerin
General Material Designation
[Book]
Other Title Information
:Methods and Protocols
First Statement of Responsibility
/ edited by Hal S. Alper
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Totowa, NJ
Name of Publisher, Distributor, etc.
: Humana Press :Imprint: Humana Press,
Date of Publication, Distribution, etc.
, 2013.
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
XII, 474 p. 61 illus., 47 illus. in color., digital.
SERIES
Series Title
(Methods in Molecular Biology, Methods and Protocols,1064-3745
Volume Designation
; 985)
NOTES PERTAINING TO PUBLICATION, DISTRIBUTION, ETC.
Text of Note
Electronic
CONTENTS NOTE
Text of Note
With the ultimate goal of systematically and robustly defining the specific perturbations necessary to alter a cellular phenotype, systems metabolic engineering has the potential to lead to a complete cell model capable of simulating cell and metabolic function as well as predicting phenotypic response to changes in media, gene knockouts/overexpressions, or the incorporation of heterologous pathways.?a In Systems Metabolic Engineering: Methods and Protocols, experts in the field describe the methodologies and approaches in the area of systems metabolic engineering and provide a step-by-step guide for their implementation. Four major tenants of this approach are addressed, including modeling and simulation, multiplexed genome engineering, a??omics technologies, and large data-set incorporation and synthesis, all elucidated through the use of model host organisms.?a Written in the highly successful Methods in Molecular Biologya?o series format, chapters include introductions on their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.?aComprehensive and cutting-edge, Systems Metabolic Engineering: Methods and Protocols serves as an ideal guide for metabolic engineers, molecular biologists, and microbiologists aiming to implement the most recent approaches available in the field.
Text of Note
Genome-Scale Model Management and Comparison -- Automated Genome Annotation and Metabolic Model Reconstruction in the SEED and Model SEED -- Metabolic Model Refinement Using Phenotypic Microarray Data -- Linking Genome-Scale Metabolic Modeling and Genome Annotation -- Resolving Cell Composition through Simple Measurements, Genome-Scale Modeling, and a Genetic Algorithm -- A Guide to Integrating Transcriptional Regulatory and Metabolic Networks Using PROM (Probabilistic Regulation of Metabolism) -- Kinetic Modeling of Metabolic Pathways: Application to Serine Biosynthesis -- Computational Tools for Guided Discovery and Engineering of Metabolic Pathways -- Retrosynthetic Design of Heterologous Pathways -- Customized Optimization of Metabolic Pathways by Combinatorial Transcriptional Engineering -- Adaptive Laboratory Evolution for Strain Engineering -- Trackable Multiplex Recombineering for Gene-Trait Mapping in E. coli -- Identification of Mutations in Evolved Bacterial Genomes -- Discovery of Post-Transcriptional Regulatory RNAs Using Next Generation Sequencing Technologies -- 13C-based Metabolic Flux Analysis: Fundamentals and Practice -- Nuclear Magnetic Resonance Methods for Metabolic Fluxomics -- Using Multiple Tracers for 13C Metabolic Flux Analysis -- Isotopically Nonstationary 13C Metabolic Flux Analysis -- Sample Preparation and Biostatistics for Integrated Genomics Approaches -- Targeted Metabolic Engineering Guided by Computational Analysis of Single Nucleotide Polymorphisms (SNPs) -- Linking RNA Measurements and Proteomics with Genome-Scale Models -- Comparative Transcriptome Analysis for Metabolic Engineering -- Merging Multiple Omics Datasets In Silico: Statistical Analyses and Data Interpretation.
SERIES
Title
Methods in Molecular Biology, Methods and Protocols,1064-3745
Volume Number
985
TOPICAL NAME USED AS SUBJECT
Chemistry
Biotechnology
Microreactors
Metabolism
Electronic books
LIBRARY OF CONGRESS CLASSIFICATION
Class number
E-BOOK
PERSONAL NAME - PRIMARY RESPONSIBILITY
Alper, Hal S.
PERSONAL NAME - SECONDARY RESPONSIBILITY
SpringerLink (Online service)
ORIGINATING SOURCE
Country
ایران
ELECTRONIC LOCATION AND ACCESS
Host name
9781627032988.pdf
Access number
عادی
Compression information
عادی
Date and Hour of Consultation and Access
9781627032988.pdf
Electronic Format Type
متن
old catalog
e
BL
1
a
Y
