Advanced free radical reactions for organic synthesis
General Material Designation
[Book]
First Statement of Responsibility
/ Hideo Togo
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Amsterdam ; London
Name of Publisher, Distributor, etc.
: Elsevier,
Date of Publication, Distribution, etc.
, 2004.
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
xii, 258 p. , ill. , 25 cm.
NOTES PERTAINING TO PUBLICATION, DISTRIBUTION, ETC.
Text of Note
Electronic
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index.
CONTENTS NOTE
Text of Note
Free radical reactions have become increasingly important and a very attractive tool in organic synthesis in the last two decades, due to their powerful, selective, specific, and mild reaction abilities. Advanced Free Radical Reactions for Organic Synthesis reviews information on all types of practical radical reactions, e.g. cyclizations, additions, hydrogen-atom abstractions, decarboxylation reactions. The book usefully provides experimental details for the most important reactions as well as numerous references to the original literature. By covering both the fundamentals and synthetic applications it is therefore suitable for both new and experienced researchers, chemists, biochemists, natural product chemists and graduate students. This title is the definitive guide to radical chemistry for all scientists. - Introduces and reviews the use of radicals to perform synthetic transformations. - Practical details are provided for the most important methods. - Numerous references to the original literature.
Text of Note
What are free radicals. -- Functional group conversion. -- Intramolecular radical cyclizations. -- Intermolecular radical addition reactions. -- Alkylation of aromatics. -- Intramolecular hydrogen-atom abstraction. -- Synthetic uses of free radicals for nucleosides and sugars: Barton-McCombie reaction. -- Barton decarboxylation reaction with N-hydroxy-2-thiopyridone. -- Free radical reactions with metal hydrides. -- Stereochemistry in free radical reactions. -- Free radicals related to biology. -- Free radicals for green chemistry.