/ edited by Jianfeng Feng, Wenjiang Fu, Fengzhu Sun
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
London
Name of Publisher, Distributor, etc.
: Springer,
Date of Publication, Distribution, etc.
, 2010.
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
1 online resource (xxv, 401 p., [13] p. of plates) , ill.
SERIES
Series Title
(Computational biology
Volume Designation
; v. 15.)
NOTES PERTAINING TO PUBLICATION, DISTRIBUTION, ETC.
Text of Note
Print
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes index.
CONTENTS NOTE
Text of Note
This unique volume surveys state-of-the-art research on statistical methods in molecular and systems biology, with contributions from leading experts in the field. Each chapter discusses theoretical aspects, applications to biological problems, and possible future developments. Topics and features: presents the use of thermodynamic models to analyze gene regulatory mechanisms; reviews major algorithms for RNA secondary structure prediction; discusses developments in the area of oligo arrays; examines the application of models of stochastic processes in nonequilibrium thermodynamics and biologi.
Text of Note
Preface; Acknowledgements; Contents; Contributors; Analysis of Combinatorial Gene Regulation with Thermodynamic Models; RNA Secondary Structure Prediction and Gene Regulation by Small RNAs; Some Critical Data Quality Control Issues of Oligoarrays; Stochastic-Process Approach to Nonequilibrium Thermodynamics and Biological Signal Transduction; Granger Causality: Theory and Applications; Transcription Factor Binding Site Identification by Phylogenetic Footprinting; Learning Network from High-Dimensional Array Data; Computational Methods for Predicting Domain-Domain Interactions.