INTERNATIONAL STANDARD BOOK NUMBER
(Number (ISBN
9780470293423 (cloth)
NATIONAL BIBLIOGRAPHY NUMBER
Country Code
IR
Number
E-3921
LANGUAGE OF THE ITEM
.Language of Text, Soundtrack etc
انگلیسی
COUNTRY OF PUBLICATION OR PRODUCTlON
Country of publication
IR
TITLE AND STATEMENT OF RESPONSIBILITY
Title Proper
BACE
General Material Designation
[Book]
Other Title Information
:lead target for orchestrated therapy of Alzheimer's disease
First Statement of Responsibility
/ edited by Varghese John
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
Hoboken, N.J.
Name of Publisher, Distributor, etc.
: John Wiley & Sons
Date of Publication, Distribution, etc.
, 2010.
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
xvi, 250 p., [16] p. of plates , ill. (some col.) , 25 cm.
NOTES PERTAINING TO PUBLICATION, DISTRIBUTION, ETC.
Text of Note
Print
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index.
CONTENTS NOTE
Text of Note
BACE : APP processing, and signal transduction in Alzheimer's disease / Dale E. Bredesen and Edward H. Koo -- Identification of BACE as a target in Alzheimer's disease / Robert L. Heinrikson and Sukanto Sinha -- BACE biological assays / Alfredo G. Tomasselli and Michael J. Bienkowski -- Peptidic, peptidomimetic, and HTS based BACE inhibitors / James P. Beck and Dustin J. Mergott -- Fragment-based approaches for identification of BACE inhibitors / Andreas Kuglstatter and Michael Hennig -- Structure-based drug design of BACE inhibitors : technical and practical aspects of preparation, 3-dimensional structure, and computational analysis / Felix F. Vajdos, Veerabahu Shanmugasundaram, and Alfredo G. Tomasselli -- Pharmacological models for preclinical testing : from mouse to dog to non-human primates / Jason L. Eriksen, Michael Paul Murphy, and Elizabeth Head -- Adsorption, distribution, metabolism, excretion (ADME), efficacy, and toxicology for BACE inhibitors / Ishrut Hussain and Emmanuel Demont -- Clinical trials for disease-modifying drugs such as BACE inhibitors / Henry H. Hsu -- Future strategies for development of novel BACE inhibitors : anti-APP B-site antibody and APP binding small molecule approaches for Alzheimer's disease / Beka Solomon ... [et al.]
TOPICAL NAME USED AS SUBJECT
Alzheimer's disease, Chemotherapy
Aspartic proteinases, Inhibitors, Therapeutic use
Amyloid beta-protein precursor
Alzheimer Disease, drug therapy
Amyloid Precursor Protein Secretases, pharmacology
Amyloid Precursor Protein Secretases, therapeutic use
LIBRARY OF CONGRESS CLASSIFICATION
Class number
RC523
Book number
.
B24
2010
PERSONAL NAME - SECONDARY RESPONSIBILITY
John, Varghese,1958-
ORIGINATING SOURCE
Country
ایران
ELECTRONIC LOCATION AND ACCESS
Host name
BACE lead target for orchestrated therapy of Alzheimer's disease edited by Varghese John
Access number
عادی
Compression information
عادی
Date and Hour of Consultation and Access
E-3921.pdf
Bits per second
3985462
Contact for access assistance
مختارزاده
Electronic Format Type
متن
File size
0
Record control number
E-3921
Public note
انگلیسی
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