NOTES PERTAINING TO PUBLICATION, DISTRIBUTION, ETC.
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INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
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Includes bibliographical references and indexes.
CONTENTS NOTE
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Overview and history of DNA typing --DNA biology review --Sample collection, DNA extraction and DNA quantitation --The polymerase chain reaction (DNA amplification) --Commonly used short tandem repeat markers and commercial kits --Biology of STRs : stutter products, non-template addition, microvariants, null alleles, and mutation rates --Forensic issues : degraded DNA, PCR inhibition, contamination, mixed samples and low copy number --Single nucleotide polymorphisms and other bi-allelic markers -- Y chromosome DNA testing -- Mitochondrial DNA analysis -- Non-human DNA testing and microbial forensics --DNA separation methods : slab-gel and capillary electrophoresis --DNA detection methods : fluorescent dyes and silver-staining --Instrumentation for STR typing : ABI 310, ABI 3100, FMBIO systems --STR genotyping issues --Laboratory validation --New technologies, automation, and expert systems --Combined DNA index system (CODIS) and the use of DNA databases --Basic genetic principles, statistics, and probability -- STR population database analyses -- Profile frequency estimates, likelihood ratios, and source attribution -- Approaches to statistical analysis of mixtures and degraded DNA -- Kinship and parentage testing -- Mass disaster DNA victim identification.