عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
NATIONAL BIBLIOGRAPHY NUMBER
Number
TLpq230741231
LANGUAGE OF THE ITEM
.Language of Text, Soundtrack etc
انگلیسی
TITLE AND STATEMENT OF RESPONSIBILITY
Title Proper
Nitrogen-15 and carbon-13 NMR studies of the interaction of cyanide ion with gold(I) drugs
General Material Designation
[Thesis]
First Statement of Responsibility
I. H. Ghazi
.PUBLICATION, DISTRIBUTION, ETC
Name of Publisher, Distributor, etc.
King Fahd University of Petroleum and Minerals (Saudi Arabia)
Date of Publication, Distribution, etc.
1993
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
124
DISSERTATION (THESIS) NOTE
Dissertation or thesis details and type of degree
M.S.
Body granting the degree
King Fahd University of Petroleum and Minerals (Saudi Arabia)
Text preceding or following the note
1993
SUMMARY OR ABSTRACT
Text of Note
N NMR studies of the interaction of N cyanide ion with gold(I)thiomalate (Autm) and gold(I)thioglucose (Autg) have been carried out at pH* 7.40. The chemical shifts of the two N containing species usd\rm Au(C\spN)\sb2\sp-usd and RS-Au-CN (where RS = tm or tg were identified. From the broadened N NMR signals, approximate lifetimes of the RS-Au-CN species were calculated. Captopril (Hcap) with gold(I) forms a 1:1 crystalline complex Au(I)cap. The exchange reactions of thiomalate and cyanide with Au(I)cap have been studied using C NMR spectroscopy. Au(I)cap forms a very high molecular weight polymer. Thiomalate and CN both bind to Au(I)cap, however, as expected, CN binds more strongly. Both the cis and trans Au(I)cap isomers were observed upon the addition of CN to A(I)cap solution. The ligand scrambling reaction of usd\rm R\sb3PAuC\spNusd to form (R3P)2Au and usd\rm Au(C\spN)\sb2\sp-usd has been studied for R = Me, Et, i-Pr, and Ph. Two P NMR resonances were observed for usd\rm R\sb3PAuCNusd and usd\rm(R\sb3P)\sb2Au\sp+usd species. However, for the N NMR, apart from usd\rm Et\sb3PAuC\spN,usd where two resonances were detected, only one averaged resonances observed for usd\rm R\sb3PAuC\spNusd (R = Me, Ph).
TOPICAL NAME USED AS SUBJECT
Analytical chemistry
Chemistry
Chemistry
Pure sciences
PERSONAL NAME - PRIMARY RESPONSIBILITY
I. H. Ghazi
ELECTRONIC LOCATION AND ACCESS
Electronic name
مطالعه متن کتاب p
[Thesis]
276903
a
Y
