Effect of Model of Care and Comorbidities on Multiple-drug-resistant Tuberculosis Treatment in Nigeria
General Material Designation
[Thesis]
First Statement of Responsibility
Comfort, Kusimo Oluremilekun
Subsequent Statement of Responsibility
Okenu, Daniel Michael
.PUBLICATION, DISTRIBUTION, ETC
Name of Publisher, Distributor, etc.
Walden University
Date of Publication, Distribution, etc.
2019
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
123
DISSERTATION (THESIS) NOTE
Dissertation or thesis details and type of degree
D.P.H.
Body granting the degree
Walden University
Text preceding or following the note
2019
SUMMARY OR ABSTRACT
Text of Note
Multidrug-resistant tuberculosis (MDR-TB) is a public health problem in several countries such as Angola, India, China, Kenya, and Nigeria. Due to the increasing high burden of MDR-TB, most of these countries do not have adequate capacities to manage MDR-TB patients effectively. This study investigated the effect of model of care; human immunodeficiency virus comorbidity; and demographic factors such as age, gender, and marital status on the treatment outcomes of MDR-TB patients in Nigeria. The study was based on the analysis of secondary data of 402 MDR-TB patients accessed from the data systems of the National Tuberculosis, Buruli Ulcer, and Leprosy Control Program. The theoretical framework for this study was the health belief model. The results of the study showed that treatment outcomes were similar for hospital and community-based models of care. Age was the only factor found to be significantly associated with treatment outcomes; age > than 40 years was a predictor of unsuccessful treatment outcomes among MDR-TB patients at a p-value of 0.026. In the multivariate logistics regression analysis, age and model of care were found to be significantly associated with treatment outcomes at p-values of 0.043 and 0.048, respectively. Marital status, gender, and HIV comorbidity were not significantly associated with treatment outcomes. Implications of the findings of this study for social change in a health care program include opportunities to help reduce the number of patients on waiting lists for MDR-TB treatment. These strategies may ultimately help to reduce the spread of MDR-TB infection as well as the mortality associated with late treatment.