immunological mechanisms and prospects for new therapies /
First Statement of Responsibility
edited by J.S.H. Gaston.
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
New York :
Name of Publisher, Distributor, etc.
Cambridge University Press,
Date of Publication, Distribution, etc.
1999.
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
1 online resource (vii, 288 pages) :
Other Physical Details
illustrations
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index.
CONTENTS NOTE
Text of Note
Ch. 1. Implications of advances in immunology for understanding the pathogenesis and treatment of rheumatic diseases -- Ch. 2. The role of T cells in autoimmune disease -- Ch. 3. The role of MHC antigens in autoimmunity -- Ch. 4. B cells: formation and structure of autoantibodies -- Ch. 5. The role of CD40 in immune responses -- Ch. 6. Manipulation of the T cell immune system via CD28 and CTLA-4 -- Ch. 7. Lymphocyte antigen receptor signal transduction -- Ch. 8. The role of adhesion mechanisms in inflammation -- Ch. 9. The regulation of apoptosis in the rheumatic disorders.
Text of Note
Ch. 10. The role of monokines in arthritis -- Ch. 11. T lymphocyte subsets in relation to autoimmune disease -- Ch. 12. Complement receptors.
0
0
SUMMARY OR ABSTRACT
Text of Note
This authoritative new volume provides a wide-ranging account of the immunological mechanisms that underlie many rheumatic diseases, such as rheumatoid arthritis, ankylosing spondylitis and SLE, and the development of effective and rational new therapies for their treatment.