Front Cover; Advances in Applied Microbiology; Copyright Page; Contents; Contributors; Chapter 1: Influence of Escherichia coli Shiga Toxin on the Mammalian Central Nervous System; I. Introduction; II. STEC Infection in Human Patients; A. Symptoms; B. Relation between D + HUS and CNS occurrences; C. CNS histopathology from autopsy; D. CNS pathology from MRI; E. CSF contents; F. Serum proteins and electrolytes; III. Animal Models; A. Types of animal models; B. Stx purification and LPS removal; C. CNS symptoms of animal models; D. CNS histopathology of animal models
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B. Pharmacokinetics and other effectsC. Adverse effects; D. Metformin in combination therapy; References; Chapter 3: Experimental Models Used to Study Human Tuberculosis; I. Introduction; II. Use of Surrogate Models to Study Tuberculosis; III. In vitro Models of Mycobacteriology; A. Fast-growing mycobacterial species; B. The M. tuberculosis complex; IV. In vivo Models of Tuberculosis; A. Macrophages and cell cultures; B. Rodent models; C. Nonhuman primates; V. The Study of Tuberculosis Pathogenesis in Human Patients; VI. Conclusions and Future Prospects; Acknowledgments; References
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C. Biosynthesis of acarbose in Actinoplanes sp. SE50/110D. Effect on hyperglycemia; III. Miglitol; A. Mechanism of action and pharmacokinetics; B. Biosynthesis and large-scale production of miglitol; C. Effect on hyperglycemia; IV. Voglibose; A. Mechanism of action and pharmacokinetics; B. Effect on hyperglycemia; V. Anthocyanins; A. Anthocyanin metabolism; B. Novel production technique; C. Mechanism of action; VI. Pine Bark Extract; VII. Other Extracts of Plant Origin; A. Known active compounds; B. Unknown active compounds; VIII. Metformin; A. Mechanism of action
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Chapter 4: Biosynthesis of Peptide Signals in Gram-Positive BacteriaI. Introduction; II. Bacillus Intracellular Signaling Peptides; A. B. subtilis CSF; B. Bacillus cereus PapR; III. Enterococcus Pheromones; IV. S. aureus Autoinducing Peptides; A. The agr system and AIP signal; B. AgrD and AgrB properties; C. AIP biosynthetic mechanism; V. Other Cyclic Peptide Signaling Systems; A. E. faecalis fsr system; B. Listeria monocytogenes agr system; C. Clostridium perfringens agr system; D. Lactobacillus plantarum agr system; VI. B. subtilis Competence Pheromones; VII. Quenching Signal Biosynthesis
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E. Pathologies by MRI (rabbit)F. CSF contents of animal models; G. Hematology and serum of animal models; IV. Similarities Between Human Patients and Animal Models; V. Relation Between Renal Failure and CNS Failure; VI. Stx Receptor, Globotriaosylceramide (Gb3) Expression in the Nervous System; VII. Stx Route from Blood to CNS Parenchyma; VIII. Future Directions; Acknowledgments; References; Chapter 2: Natural Products for Type II Diabetes Treatment; I. Introduction; II. Acarbose; A. Mechanism of action and pharmacokinetics; B. Manufacturing of acarbose
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SUMMARY OR ABSTRACT
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Published since 1959, Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology. The series contains comprehensive reviews of the most current research in applied microbiology. Recent areas covered include bacterial diversity in the human gut, protozoan grazing of freshwater biofilms, metals in yeast fermentation processes and the interpretation of host-pathogen dialogue through microarrays. Eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building syndrome. Impact factor for 2008: 1.658. * Contributions from leading authorities and industry experts * Informs and updates on all the latest developments in the field * Reference and guide for scientists and specialists involved in advancements in applied microbiology.