Applications of toxicogenomic technologies to predictive toxicology and risk assessment /
General Material Designation
[Book]
First Statement of Responsibility
Committee on Applications of Toxicogenomic Technologies to Predictive Toxicology ; Board on Environmental Studies and Toxicology ; Board on Life Studies ; Division on Earth and Life Studies ; National Research Council of the National Academies.
Includes bibliographical references (pages 213-254).
CONTENTS NOTE
Text of Note
Introduction -- Toxicogenomic technologies -- Experimental design and data analysis -- Application to exposure assessment -- Application to hazard screening -- Application to analyzing variation in human susceptibility -- Application to the study of mechanisms of action -- Other potential applications of toxicogenomic technologies to risk assessment -- Validation -- Sample and data collection and analysis -- Ethical, legal, and social issues -- Conculsions and recommendations.
0
SUMMARY OR ABSTRACT
Text of Note
The new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identify the benefits of toxicogenomics, the challenges to achieving them, and potential approaches to overcoming such challenges. The report concludes that realizing the potential of toxicogenomics to improve public health decisions will require a concerted effort to generate data, make use of existing data, and study data in new ways--an effort requiring funding, interagency coordination, and data management strategies.
OTHER EDITION IN ANOTHER MEDIUM
Title
Applications of toxicogenomic technologies to predictive toxicology and risk assessment.
International Standard Book Number
9780309112987
TOPICAL NAME USED AS SUBJECT
Carcinogenesis.
DNA microarrays-- Statistical methods.
Genetic toxicology.
Health risk assessment.
Hazardous Substances-- toxicity.
Models, Statistical.
Oligonucleotide Array Sequence Analysis.
Risk Assessment.
Toxicogenetics-- methods.
Cancérogenèse.
Puces à ADN-- Méthodes statistiques.
Risques pour la santé-- Évaluation.
Toxicologie génétique.
Carcinogenesis.
DNA microarrays-- Statistical methods.
Genetic toxicology.
HEALTH & FITNESS-- Diseases-- Genetic.
Health risk assessment.
MEDICAL-- Genetics.
(SUBJECT CATEGORY (Provisional
HEA-- 039060
K
MED-- 107000
DEWEY DECIMAL CLASSIFICATION
Number
616/
.
042
Edition
22
LIBRARY OF CONGRESS CLASSIFICATION
Class number
RA1224
.
3
Book number
.
N375
2007eb
OTHER CLASS NUMBERS
Class number
2008
B-271
Class number
QV
38
Book Number
A6523
2007
CORPORATE BODY NAME - PRIMARY RESPONSIBILITY
National Research Council (U.S.)., Committee on Applications of Toxicogenomic Technologies to Predictive Toxicology.
CORPORATE BODY NAME - ALTERNATIVE RESPONSIBILITY
National Research Council (U.S.)., Committee on Applications of Toxicogenomic Technologies to Predictive Toxicology.