عنوان

Heart rate slowing by IF current inhibition /

(Number (ISBN

1429468343

(Number (ISBN

3318013811

(Number (ISBN

9781429468343

(Number (ISBN

9783318013818

Erroneous ISBN

3805581602

Erroneous ISBN

9783805581608

Number

b766684

Title Proper

Heart rate slowing by IF current inhibition /

General Material Designation

[Book]

First Statement of Responsibility

volume editors, John Camm, Michal Tendera.

Place of Publication, Distribution, etc.

New York :

Name of Publisher, Distributor, etc.

Karger,

Date of Publication, Distribution, etc.

2006.

Specific Material Designation and Extent of Item

1 online resource (viii, 115 pages).

Series Title

Advances in cardiology,

Volume Designation

v. 43

ISSN of Series

0065-2326 ;

Text of Note

Includes bibliographical references and indexes.

Text of Note

Heart rate: a risk factor for cardiac diseases and outcomes? Pathophysiology of cardiac diseases and the potential role of heart rate slowing / Lanza, G.A., Fox, K., Crea, F. -- IF current inhibition: cellular basis and physiology / Mangoni, M.E., Marger, L., Nargeot, J. -- Heart rate reduction by pharmacological IF current inhibition / Cargnoni, A. [and others] -- Clinical perspectives of heart rate slowing for coronary event reduction and heart failure / Danchin, N., Kadri, Z. -- Clinical effect of 'pure' heart rate slowing with a prototype IF current inhibitor: placebo-controlled experience with ivabradine / Borer, J.S. -- Heart rate slowing versus other pharmacological antianginal strategies. Results of comparative studies / Diaz, A., Tardif, J.-C. -- Novel IF current inhibitor ivabradine: safety considerations / Savelieva, I., Camm, A.J. -- Heart rate slowing for myocardial dysfunction/heart failure. Rationale and preclinical studies / Mulder, P., Thuillez, C. -- Future directions: what data do we need? / Tendera, M.

0

Text of Note

This book unfolds the history of the discovery of the transmembrane channel which is responsible for the 'funny' or If current, the primary modulator of heart rate. Inhibition of this current leads to slowing of the heart rate, which is an important component of the successful management of angina pectoris. Recently, Ivabradine, a specific and selective inhibitor of the If current, has been developed as an antianginal agent which has been shown to be at least as effective as both beta-blockers and calcium channel blockers for the treatment of angina. The development, efficacy and complications.

Source for Acquisition/Subscription Address

S. Karger AG

Stock Number

978-3-8055-8160-8

Title

Heart rate slowing by IF current inhibition.

Angina pectoris.

Heart beat.

Heart conduction system.

Ion channels.

Heart Diseases-- drug therapy.

Heart Rate-- drug effects.

Heart Rate-- physiology.

Ion Channels-- drug effects.

Membrane Potentials-- drug effects.

Angina pectoris-- Herzfrequenz-- Inhibition-- Pharmakotherapie, Aufsatzsammlung.

Angina pectoris.

HEALTH & FITNESS-- Diseases-- Heart.

Heart beat.

Heart conduction system.

Herzfrequenz-- Inhibition-- Angina pectoris-- Pharmakotherapie, Aufsatzsammlung.

Ion channels.

MEDICAL-- Cardiology.

Pharmakotherapie-- Herzfrequenz-- Inhibition-- Angina pectoris, Aufsatzsammlung.

HEA-- 039080

MED-- 010000

Number

Edition

Class number

Book number

Class number

Class number

Book Number

Book Number

Camm, A. John.

Tendera, Micha?

Date of Transaction

20201206115737.0

Cataloguing Rules (Descriptive Conventions))

pn

Electronic name

[Book]

Y