Part I. The molecular design of life -- 1. Prelude -- 2. Biochemical evolution -- 3. Protein structure and function -- 4. Exploring proteins -- 5. RNA, DNA, and the flow of genetic information -- 6. Exploring genes -- 7. Exploring evolution (including bioinformatics) -- 8. Enzymes: Basic concepts and kinetics -- 9. Catalytic strategies -- 10. Regulatory strategies: Enzymes and hemoglobin -- 11. Carbohydrates -- 12. Lipids and cell membranes -- 13. Membrane channels and pumps -- Part II. Transducing and storing energy -- 14. Metabolism: Basic concepts and design -- 15. Signal-transduction pathways: An introduction to information metabolism -- 16. Glycolysis and gluconeogenesis -- 17. The citric acid cycle -- 18. Oxidative phosphorylation -- 19. The light reactions of photosynthesis -- 20. The Calvin cycle and the pentose phosphate pathway -- 21. Glycogen metabolism -- 22. Fatty acid metabolism -- 23. Protein turnover and amino acid catabolism -- Part III. Synthesizing the molecules of life -- 24. The biosynthesis of amino acids -- 25. Nucleotide biosynthesis -- 26. The biosynthesis of membrane lipids and steroids -- 27. DNA replication, recombination, and repair -- 28. RNA synthesis and splicing -- 29. Protein synthesis -- 30. The integration of metabolism -- 31. The control of gene expression -- Part IV. Responding to environmental changes -- 32. Sensory systems -- 33. The immune system -- 34. Molecular motors.