Perspectives on arrhythmogenesis, antiarrhythmic strategies, and sudden cardiac death / Peter M. Spooner -- pt. 1. Ion channels to action potentials -- Cardiac membrane and action potentials / Dan M. Roden -- Cardiac ion channels / Harry A. Fozzard -- Cardiac ion pumps and ion exchangers / Arnold Schwartz -- Regulation of cardiac ion channels and transporters / H. Criss Hartzell -- Molecular diversity and distribution of cardiac ion channels / Harold C. Strauss -- pt. 2. Action potentials to tissue activation -- Sinoatrial node and impulse initiation / Richard B. Robinson -- Intracardiac cell communication and gap junctions / Jeffrey E. Saffitz -- Impulse conduction: continuous and discontinuous / Charles Antzelevitch -- Networks: fundamental properties and models / Ronald W. Joyner -- Atrioventricular conduction / Ralph Lazzara -- Ca2+ and arrhythmias / Henk E.D.J. ter Keurs -- pt. 3. Tissue activation to cardiac rhythm -- The electrocardiogram and elctrophysiological analysis / David M. Mirvis -- Global behaviors of cardiac activation / Yoram Rudy -- Mapping and invasive analysis / Robert L. Lux -- pt. 4. Arrhythmias: origins and mechanisms -- Automaticity and triggered activity / Marc A. Vos -- Reentry / Michiel J. Janse -- Atrial fibrillation / Albert L. Waldo -- Ventricular fibrillation and defibrillation / Stephen M. Dillon -- Origins, classification, and significance of ventricular arrhythmias / Robert J. Myerburg -- pt. 5. Therapeutic strategies and future directions -- Cardiac pacemakers / Adam Zivin -- Implantable cardioverter defibrillators / Adam Zivin -- Remodeling: structural and electrical considerations / Gordon R. Tomaselli -- Transgenic electrophysiology and small animal models / Amit Rakhit -- Genetics approaches and familial arrhythmias / Jeffrey A. Towbin -- New directions for antiarrhythmic drug development based on molecular approaches to arrhythmogenesis / Eduardo Marbán -- Ablation therapy of cardiac arrhythmias / Douglas P. Zipes -- Risk identification by noninvasive markers of cardiac vulnerability / Richard L. Verrier -- Sudden cardiac death and its prevention / Christine M. Albert.