Front Cover; Advances in Immunology, Volume 43; Copyright Page; Contents; Chapter 1. The Chemistry ond Mechanism of Antibody Binding to Protein Antigens; I. Introduction; II. Criteria for Systematic Studies; III. Structural Chemistry from X-ray Crystallography; IV. Defining the Chemistry of Antigenic Recognition; V. Defining the Mechanisms of Antigenic Recognition; VI . Dominant Epitopes and Collective Response; VII. Evaluation of Predictive Methods; VIII. An Experimental Approach to the Design of Antipeptide Antibodies; IX. Frequency Data for Individual Amino Acids in Protein Epitopes.
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V. Possible Mechanisms Mediating Transcriptional Regulation of Immunoglobulin GenesVI. T Cell Receptor Gene Expression; References; Chapter 6. Molecular Aspects of Receptors and Binding Factors for IgE; I. Introduction; II. Sites on IgE Interacting with Receptors; III. The Mast-Cell Specific Receptor; IV. Immunoregulatory Fce, Receptors and IgE-Binding Factors; V. Surface Receptors on Monocytes, Eosinophils, and Platelets; VI. Other IgE-Binding Proteins; References; Index; Content of Recent Volume; Color Plates.
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VIII. Summary and HypothesisReferences; Chapter 4. Specificity of the T Cell Receptor for Antigen; I. Introduction; II. Nature of the Determinant Recognized by T Cells; III. Studies on the Specificity of T Cells for Peptide Antigens; V. TCR Combining Site; VI. Strategies of Immune Recognition; References; Chapter 5. Transcriptional Controlling Elements in the Immunoglobulin and T Cell Receptor Loci; I. Introduction; II. Immunoglobulin Gene Expression; III. Immunoglobulin Transcriptional Enhancer Elements; IV. Immunoglobulin Promotor Elements.
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X. Overview of Chemistry and Binding EnergyReferences; Chapter 2. Structure of Antibody-Antigen Complexes: Implications for Immune Recognition; I. Introduction; II. Principles of Protein-Protein Interactions; III. Antigen Receptor Structure; IV. Antigens; V. Three-Dimensional Structures of Complexes; VI. The Interface Adaptor Hypothesis; References; Chapter 3. The?d T Cell Receptor; I. Introduction: Immunological Antigen Receptors; II. T Cell Receptor (TCR)? Genes; III. TCR?d Proteins; IV. TCR d Genes; V. Phenotype and Distribution of TCR?d Lymphocytes; VI. Ontogeny of TCR?d.