Front Cover; Advances in Immunology; Copyright Page; Contents; Contributors; Chapter 1. Transcriptional Regulation in Neutrophils: Teaching Old Cells New Tricks; I. Introduction; II. The STAT Family of Transcription Factors; III. The NF-kB Family of Transcription Factors; IV. Other Transcription Factors Potentially Involved in Neutrophil Activation; V. Conclusion; References; Chapter 2. Tumor Vaccines; I. Introduction; II. Tumor Antigens; III. Vaccination Strategies; IV. Concluding Summary; References; Chapter 3. Immunotherapy of Allergic Disease; I. Introduction
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Chapter 4. Interactions of Immunoglobulins Outside the Antigen-Combining SiteI. Introduction; II. Fc Receptor-Binding Sites; III. Complement-Binding Sites; IV. Proteins and Peptides Reacting with Fc; V. Proteins Reacting with Fab; VI. Lectins; VII. Proteins from Pathogens Reacting with Immunoglobulins; VIII. The Promiscuity of the Cy2-Cy3 Interface; IX. Concluding Remarks; References; Chapter 5. The Role of Antibodies in Mouse Models of Rheumatoid Arthritis, and Relevance to Human Disease; I. Rheumatoid Arthritis: Clinical and Pathological Features; II. RA: Theories of Pathogenesis
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II. Time Course and Pathophysiology of Type I AllergyIII. Possible Targets for Immunotherapy of Allergic Disease; IV. Allergen-Specific Immunotherapy; V. Possible Mechanisms Underlying Allergen-Specific Immunotherapy; VI. Modifications of Traditional, Allergen Extract-Based Immunotherapy; VII. Possible Improvement of Immunotherapy by Using Recombinant Allergens; VIII. Genetic Engineering of Modified Allergens for Immunotherapy; IX. Clinical Results with Modified Recombinant Allergens; X. Formulating Prophylactic Allergy Vaccines; References
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III. Effector Mechanisms of Antibody-Mediated DiseaseIV. Animal Models: General Considerations; V. Collagen-Induced Arthritis; VI. Antigen-Induced Arthritis; VII. Proteoglycan-Induced Arthritis; VIII. Streptococcal Cell Wall Arthritis; IX. Pristane-Induced Arthritis; X. Zymosan-Induced Arthritis; XI. Adjuvant Arthritis; XII. K/BxN (Anti-GPI-Mediated) Arthritis; XIII. Arthritis in the Ipr Mouse; XIV. HTLV Transgenic Mouse; XV. Human TNF Transgenic Mouse; XVI. IL-1ra Knockout Mouse; XVII. Mutant IL-6 Receptor Mouse; XVIII. Other Models; XIX. Summary of Mouse Models; XX. Relevance to RA
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SUMMARY OR ABSTRACT
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Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.