edited by Jeffrey C. Hall, Jay C. Dunlap, Theodore Friedmann, Francesco Giannelli.
Volume Designation
Volume 38 /
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
New York, N.Y. :
Name of Publisher, Distributor, etc.
Academic Press,
Date of Publication, Distribution, etc.
1998.
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
1 online resource (vii, 225 pages) :
Other Physical Details
illustrations, diagrams.
SERIES
Series Title
Advances in genetics ;
Volume Designation
38
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index.
CONTENTS NOTE
Text of Note
Front Cover; Advances in Genetics, Volume 38; Copyright Page; Contents; Contributors; Chapter 1. Body Plan Genes and Human Malformation; I. Introduction; II. Establishing the Body Axes; III. Patterning the Limb; IV. Patterning the Ocular Anlage; V. Patterning the Tooth Anlage; References; Chapter 2. Molecular Genetics of the Hereditary Ataxias; I. Introduction; II. The Autosomal Dominant Progressive Ataxias; III. Friedreich Ataxia; References; Chapter 3. The Minute Genes in Drosophila and Their Molecular Functions; I. Introduction; II. Historical Review.
Text of Note
III. Minutes as Genetic Tools in Studies of Growth and DevelopmentIV. Minutes and the Protein Synthesis Theory; V. Conclusions and Prospects; References; Chapter 4. Genetics of Biological Rhythms in Drosophila; I. Introduction; II. Chronogenetics; III. Chronogenetic Biology; IV. A Final Chronogenetic Thought; References; Chapter 5. DNA Breakage and Repair; I. Introduction; II. Formation of DNA Strand Breaks; III. Mechanisms for the Repair of DNA DSBs; IV. Identification of Genes Required for NHEJ; V. Characterization of Proteins Involved in NHEJ by Biochemical, Molecular, and Genetic Analysis.
Text of Note
VI. DNA-PK as a Protein KinaseVII. The Mechanism of NHEJ; VIII. The Contribution of NHEJ and HR to DSB Rejoining in Yeast versus Mammalian Cells; IX. DNA-PK-Defective Mice; X. Radiosensitivity and Immune Deficiency; XI. A Model for NHEJ; XII. Summary; References; Index.
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SUMMARY OR ABSTRACT
Text of Note
This volume of Advances in Genetics furthers the serial's goal of presenting topics of interest to both human and molecular geneticists. Topics of interest in this volume include: Expression patterns of regulatory genes and the role they play in development Hereditary ataxias and specific disease states where the genetic defect has been identified Minute genes, their mutations, and their molecular function in Drosophila The genetics and molecular biology of rhythm mutants and clock molecules Double strand breaks in DNA and their repair mechanisms Key Features * Expression patterns of regulatory genes and the role they play in development * Hereditary ataxias and specific disease states where the genetic defect has been identified * Minute genes, their mutations, and their molecular function in Drosophila * The genetics and molecular biology of rhythm mutants and clock molecules * Double-strand breaks in DNA and their repair mechanisms and lack of repair mechanisms resulting in human disorders.