عنوان

Peptide nucleic acids :

(Number (ISBN

0896039765

(Number (ISBN

1280830743

(Number (ISBN

1592592902

(Number (ISBN

6610830746

(Number (ISBN

9780896039766

(Number (ISBN

9781280830747

(Number (ISBN

9781592592906

(Number (ISBN

9786610830749

Number

b713053

Title Proper

Peptide nucleic acids :

General Material Designation

[Book]

Other Title Information

methods and protocols /

First Statement of Responsibility

edited by Peter E. Nielsen.

Place of Publication, Distribution, etc.

Totowa, N.J. :

Name of Publisher, Distributor, etc.

Humana Press,

Date of Publication, Distribution, etc.

©2002.

Specific Material Designation and Extent of Item

1 online resource (x, 274 pages) :

Other Physical Details

illustrations

Series Title

Methods in molecular biology ;

Volume Designation

v. 208

Text of Note

Includes bibliographical references and index.

Text of Note

PNA technology / Peter E. Nielsen -- Solid phase synthesis of PNA oligomers / Frederik Beck -- Synthesis of PNA-peptide conjugates / Satish Kumar Awasthi -- Parallel synthesis of PNA-peptide conjugate libraries / Satish Kumar Awasthi -- Thermodynamics of PNA interactions with DNA and RNA / Tommi Ratilainen -- Measurement of PNA binding to double-stranded DNA / Thomas Bentin -- PNA-mediated immobilization of supercoiled DNA / Thomas Bentin -- PNA openers and their applications /Vadim V. Demidov -- Colorimetric detection of PNA-DNA hybridization using cyanine dyes / Miaomiao Wang -- PNA-medicated PCR clamping: applications and methods / Deborah G. Murdock -- PNA clamping techniques for the determination of oncogene mutations / Marcus Schuermann -- PNA fluorescent in situ hybridization for rapid microbiology and cytogenetic analysis / Brett Williams -- Detection of point mutations using PNA-containing electrophoresis matrices / Gabor L. Igloi -- Lipid-mediated introduction of peptide nucleic acids into cells / Dwaine A. Braasch -- Synthesis of cell-penetrating peptide-PNA constructs / Margus Pooga -- Antisense inhibition of bacterial gene expression and cell growth / Liam Good -- In vitro transcription from peptide nucleic acid/DNA strand displacement loops / Niels Erik Mollegaard -- In vitro and in vivo studies on pharmacokinetics and metabolism of PNA constructs in rodents / Edward Kristensen.

0

Text of Note

Peptide nucleic acid (PNA) technology continues to grow in importance throughout molecular biology, genetic diagnostics, and molecular medicine. In Peptide Nucleic Acids: Methods and Protocols, Peter Eigil Nielsen has assembled a critically evaluated collection of PNA protocols that are either already well established around the world, such as PCR-clamping and in situ hybridization, or that display promise of significant future impact. Basic methods for PNA oligomer synthesis and analysis have also been included. Written by experts with hands-on experience in the methods they describe, these readily reproducible protocols contain detailed step-by-step instructions, tips on avoiding pitfalls and on extending the method to other situations, and introductory material explaining the theory behind the process. Up-to-date and highly practical, Peptide Nucleic Acids: Methods and Protocols provides for both novice and experienced researchers a thorough and easy introduction to the optimal use of today's PNA technology across a wide variety of fields, including molecular biology, medicinal chemistry, genetic diagnostics, and drug development.

Title

Peptide nucleic acids.

International Standard Book Number

9780896039766

Title

Springer Protocols

DNA-- Derivatives.

Peptides-- Derivatives.

Peptide Nucleic Acids.

ADN-- Dérivés.

Peptides-- Dérivés.

DNA-- Derivatives.

Nucleïnezuren.

Peptiden.

SCIENCE-- Life Sciences-- Molecular Biology.

Wetenschappelijke technieken.

PSB.

SCI-- 049000

Number

Edition

Class number

Book number

Class number

Class number

Book Number

Book Number

Nielsen, Peter E.,1951-

Date of Transaction

20201208032929.0

Cataloguing Rules (Descriptive Conventions))

pn

Electronic name

[Book]

Y