Preface; Contents; Contributors; 1 Regulation and Control of Cell -- Cell Fusions; 2 Retroviruses and Cell Fusions: Overview; 3 Retroviral Membrane Fusions: Regulation by Proteolytic Processing and Cellular Factors; 4 A Comparative Portrait of Retroviral Fusogens and Syncytins; 5 Syncytins: Molecular Aspects; 6 Role of the Actin Cytoskeleton Within FuRMAS During Drosophila Myoblast Fusion and First Functionally Conserved Factors in Vertebrates; 7 Role of CD9 in Sperm-Egg Fusion and Its General Role in Fusion Phenomena; 8 Gamete Binding and Fusion.
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SUMMARY OR ABSTRACT
Text of Note
Cell fusions are important to fertilization, placentation, development of skeletal muscle and bone, calcium homeostasis and the immune defence system. Additionally, cell fusions participate in tissue repair and may be important to cancer development, progression and therapy. A large number of factors regulate cell fusions, including receptors and ligands, membrane domain organizing proteins, proteases, signaling molecules and fusogenic proteins that bring membranes close together. In the present volume, we interrogate what mechanisms that may be important to cell fusions in mammals and what me.