Origin and nature of chronic lymphocytic leukemia B cells / Nicolas Chiorazzi and Manlio Ferrarini -- Gene expression profiling in the study of CLL / Ulf Klein -- Molecular pathogenesis / Arianna Bottoni, Carlo M. Croce, and George A. Calin -- Chronic lymphocytic leukemia and the B cell receptor / Marta Muzio and Federico Caligaris-Cappio -- Etiology of CLL : the role of MBL / Paolo Ghia and Andrew C. Rawstron -- Apoptosis dysregulation in CLL / Victoria Del Gaizo Moore and Anthony Letai -- Differential diagnosis, staging, and prognostic factors / Thorsten Zenz, Hartmut Dohner, and Stephan Stilgenbauer -- Frontline therapy of chronic lymphocytic leukemia / Barbara Eichhorst and Michael Hallek -- Treatment of patients with relapsed or refractory chronic lymphocytic leukemia / Karen W.L. Yee, Michael J. Keating, and Susan M. O'Brien -- New therapies in chronic lymphocytic leukemia / John C. Byrd [and others] -- Stem cell transplantation in CLL / John G. Gribben -- Gene therapy, vaccines, and immune modulation / William G. Wierda -- Prolymphocytic leukemias / Claire E. Dearden -- CLL specific complications : autoimmunity and Richter's transformation / Dennis A. Carney and John F. Seymour -- Infectious complications in patients with chronic lymphocytic leukemia / Elias Anaissie.
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SUMMARY OR ABSTRACT
Text of Note
Up-to-date picture of CLL and how to better treat patients inflicted with the disease. New information on developments in the molecular pathogenesis of this disease impacts how physicians approach and treat patients with CLL. The various predisposing factors for the disease are addressed along with current and future treatment modalities and recommended standards of care.