عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
NATIONAL BIBLIOGRAPHY NUMBER
Number
LA8w1801m8
LANGUAGE OF THE ITEM
.Language of Text, Soundtrack etc
انگلیسی
TITLE AND STATEMENT OF RESPONSIBILITY
Title Proper
Bromethalin toxicosis--evaluation of aminophylline treatment and an epidemiolgic assessment
General Material Designation
[Article]
First Statement of Responsibility
Dorman, David C.; Parker, Alan J.; Buck, William B.
SUMMARY OR ABSTRACT
Text of Note
The compound bromethalin is described and characterized in terms of mode of action when used as a rodenticide. It is hypothesized that an antimetabolite which inhibits the conversion of bromethalin to its desmethylbromethalin metabolite could represent a potential treatment for bromethalin toxicosis. An ideal antimetabolite of bromethalin is described, and based on these considerations, aminophylline (theophylline ethylenediamine) was chosen as a potential antimetabolite. In lab trials, aminophylline was administered to rats given a lethal dose of bromethalin, but it was not effective in prolonging rat survival. However, it did result in mean survival time being increase to nearly double. Further studies aminophylline or similar drugs may results in identifying a suitable treatment for bromethalin-induced toxic syndrome.
SET
Date of Publication
1990
Title
Proceedings of the Vertebrate Pest Conference
Volume Number
14
PERSONAL NAME - PRIMARY RESPONSIBILITY
Entry Element
Dorman, David C.; Parker, Alan J.; Buck, William B.
ELECTRONIC LOCATION AND ACCESS
Electronic name
مطالعه متن کتاب [Article]
275578
a
Y
